74497-02-2合成路线 (共 11739 条)
反应条件
1: With trichlorosilane in dichloromethane T=0°C; 0.5 h; Inert atmosphere; 2: With N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-N-methylpicolinamide in dichloromethane T=0°C; 72 h; Inert atmosphere; 3: With sodium hydrogencarbonate in dichloromethane; water Saturated solution; optical yield given as percent eeenantioselective reaction;
参考文献
Guizzetti, Stefania; Benaglia, Maurizio; Cozzi, Franco; Annunziata, Rita
Tetrahedron, 2009 , vol. 65, # 32 p. 6354 - 6363
反应条件
1: With [Pd(dppe)(H2O)2](TfO)2 in 1,4-dioxane T=80°C; 18 h; 2: With silica gel in dichloromethane T=20°C; 2 h;
参考文献
Shimada, Tomohiro; Bajracharya, Gan B.; Yamamoto, Yoshinori
European Journal of Organic Chemistry, 2005 , # 1 p. 59 - 62
参考文献
Wachter
Chemische Berichte, 1892 , vol. 25, p. 1732
反应条件
Rapp TentaGel S RAM resin; water; tris-(o-tolyl)phosphine; trifluoroacetic acid; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium(0) 1.) EDC, DMF; 2.) dioxane, 70-80 deg C, 16-20 h; 3.) 40 min; Yield given. Multistep reaction;
参考文献
Willoughby, Christopher A.; Chapman, Kevin T.
Tetrahedron Letters, 1996 , vol. 37, # 40 p. 7181 - 7184
反应条件
T=160 - 180°C; beim Behandeln von Anilin-hydrochlorid;
参考文献
Brunner; Seeger; Dittrich
Monatshefte fuer Chemie, 1924 , vol. 45, p. 72
参考文献
Holleman
Recueil des Travaux Chimiques des Pays-Bas, 1891 , vol. 10, p. 70
Chemische Berichte, 1890 , vol. 23, p. 3000
参考文献
Holleman
Recueil des Travaux Chimiques des Pays-Bas, 1891 , vol. 10, p. 70
Chemische Berichte, 1890 , vol. 23, p. 3000
参考文献
Peak
Journal of the Chemical Society, 1952 , p. 215,220
参考文献
Banfield et al.
Austral. J. scient. Res., 1948 , vol. <A> 1, p. 330,338
参考文献
Brunner; Seeger; Dittrich
Monatshefte fuer Chemie, 1924 , vol. 45, p. 72