74497-02-2合成路线 （共 11739 条）
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Toyoda, Tatsuo; Sasakura, Kazuyuki; Sugasawa, Tsutomu
Tetrahedron Letters, 1980 , vol. 21, p. 173 - 176
参考文献
Klinger
Justus Liebigs Annalen der Chemie, 1912 , vol. 389, p. 250
Justus Liebigs Annalen der Chemie, 1912 , vol. 390, p. 375
参考文献
Klinger
Justus Liebigs Annalen der Chemie, 1912 , vol. 389, p. 250
Justus Liebigs Annalen der Chemie, 1912 , vol. 390, p. 375
反应条件
1: 1) NaNO2 / 1) H2O, conc. HCl, 0 degC, 2) 2 N NaOH, -10 degC, 1 min
2: 85 percent / 1 N HCl / methanol / 5 h / Ambient temperature
View Scheme
参考文献
Neugebauer, Franz Alfred; Fischer, Hans
Chemische Berichte, 1980 , vol. 113, # 4 p. 1226 - 1234
反应条件
1: 1) NaNO2 / 1) H2O, conc. HCl, 0 degC, 2) 2 N NaOH, -10 degC, 1 min
2: 85 percent / 1 N HCl / methanol / 5 h / Ambient temperature
3: 70 percent / NH2OH*HCl, 2 N NaOH / ethanol / Heating
View Scheme
参考文献
Neugebauer, Franz Alfred; Fischer, Hans
Chemische Berichte, 1980 , vol. 113, # 4 p. 1226 - 1234
反应条件
1: 1) NaNO2 / 1) H2O, conc. HCl, 0 degC, 2) 2 N NaOH, -10 degC, 1 min
2: 85 percent / 1 N HCl / methanol / 5 h / Ambient temperature
3: 70 percent / NH2OH*HCl, 2 N NaOH / ethanol / Heating
4: 43 percent / Pb(O2CCH3)4 / CH2Cl2
View Scheme
参考文献
Neugebauer, Franz Alfred; Fischer, Hans
Chemische Berichte, 1980 , vol. 113, # 4 p. 1226 - 1234
反应条件
1: 1) NaNO2 / 1) H2O, conc. HCl, 0 degC, 2) 2 N NaOH, -10 degC, 1 min
2: 85 percent / 1 N HCl / methanol / 5 h / Ambient temperature
3: 70 percent / NH2OH*HCl, 2 N NaOH / ethanol / Heating
4: 70 percent / acetic anhydride / acetic acid / Heating
View Scheme
参考文献
Neugebauer, Franz Alfred; Fischer, Hans
Chemische Berichte, 1980 , vol. 113, # 4 p. 1226 - 1234
反应条件
3: LiAlH4 / tetrahydrofuran
View Scheme
参考文献
Sato, Susumu; Tomita, Kuniyuki; Fujita, Hiroshi; Sato, Yosunobu
Heterocycles, 1984 , vol. 22, # 5 p. 1045 - 1048
反应条件
formic acid; sodium cyanoborohydride in acetonitrile
Yield given;
参考文献
Swank, Darrel W.; Lambeth, David O.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1713 - 1715
反应条件
1: in tetrachloromethane
T=-10°C;
2: With K10 clay impregnated with copper(II) nitrate; acetic anhydride in tetrachloromethane
T=20°C; 2.5 h;
参考文献
Fonseca, Tatiana; Gigante, Barbara; Gilchrist, Thomas L
Tetrahedron, 2001 , vol. 57, # 9 p. 1793 - 1799
