74497-02-2合成路线 （共 11739 条）
反应条件
T=18°C; Rate constant;
参考文献
Jensen et al.
Acta Chemica Scandinavica (1947-1973), 1952 , vol. 6, p. 1073,1077, 1078
反应条件
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene
T=100°C; 17 h;
参考文献
Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Estevinho, Leticia M.; Queiroz, Maria-Joao R.P.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 23 p. 5831 - 5833
反应条件
in ethanol
T=20°C; 20 h;
参考文献
Lee, Hyun-Jung; Kim, Jin Sung; Park, Se-Young; Suh, Myung-Eun; Kim, Hwa Jung; Seo, Eun-Kyung; Lee, Chong-Ock
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 7 p. 1623 - 1628
反应条件
1.1: 4-methyl-morpholine; copper(II) oxide / 1,4-dioxane / 16 h / |Reflux; |Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 20 °C / |Cooling with ice
2.2: 0 °C
3.1: potassium hydroxide; ethanol / water / |Reflux
4.1: tetrahydrofuran / 0.5 h / |Inert atmosphere
5.1: triethylamine / tetrahydrofuran / 20 °C / |Inert atmosphere
6.1: [bis(acetoxy)iodo]benzene / acetonitrile / 0.5 h / 20 °C / |Cooling with ice
7.1: palladium 10 on activated carbon; acetic acid; hydrogen / 36 h / 70 °C
View Scheme
参考文献
Li, Xuming; Yang, Liu; Zhang, Xiang; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang
Journal of Organic Chemistry, 2014 , vol. 79, # 3 p. 955 - 962
反应条件
silica gel
0.0125 h; Microwave irradiationneat (no solvent);
参考文献
Batra, Manoj Kumar; Batra, Chhavi; Ojha
Journal of the Indian Chemical Society, 2008 , vol. 85, # 12 p. 1205 - 1210
参考文献
Schmitt; Andresen
Journal fuer Praktische Chemie (Leipzig), 1881 , vol. <2> 24, p. 434
参考文献
Niemayer
Justus Liebigs Annalen der Chemie, 1885 , vol. 228, p. 338
参考文献
Fries; Ochwat
Chemische Berichte, 1923 , vol. 56, p. 1298
参考文献
Makarova,A.N.; Berlin,A.Ya.
Zhurnal Organicheskoi Khimii, 1965 , vol. 1, # 12 p. 2159 - 2164,2201 - 2205
反应条件
hydrogenchloride; acetic acid
das Filtrat wird mit Wasser gefaellt;
参考文献
Niemeyer
Justus Liebigs Annalen der Chemie, 1885 , vol. 228, p. 324
