4-甲氧基苯基氨基甲酸乙酯合成路线 （共 33 条）
反应条件
ethylmagnesium bromide in tetrahydrofuran; dichloromethane 5 deg C, then 48h reflux;
参考文献
Basha, Anwer
Tetrahedron Letters, 1988 , vol. 29, # 21 p. 2525 - 2526
反应条件
triethylamine T=80 - 120°C; 2 h;
参考文献
Fauron,C.; Douzon,C.
Chimica Therapeutica, 1973 , vol. 8, p. 143 - 147
反应条件
1: With trifluoroacetic acid 1 h; Heating; 2: With potassium hydroxide; potassium hexacyanoferrate(III) in ethanol; water 4 h; Heating;
参考文献
Chilin, Adriana; Marzaro, Giovanni; Zanatta, Samuele; Barbieri, Vera; Pastorini, Giovanni; Manzini, Paolo; Guiotto, Adriano
Tetrahedron, 2006 , vol. 62, # 52 p. 12351 - 12356
反应条件
1: TFA / 0.17 h / 110 °C / microwave irradiation 2: K3Fe(CN)6; KOH / H2O; ethanol / 0.67 h / 100 °C / microwave irradiation View Scheme
参考文献
Chilin, Adriana; Marzaro, Giovanni; Zanatta, Samuele; Guiotto, Adriano
Tetrahedron Letters, 2007 , vol. 48, # 18 p. 3229 - 3231
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Heating / reflux;
参考文献
Dupont Pharmaceuticals
Patent: US2006/25407 A1, 2006 ;
Location in patent: Page/Page column 46 ;
反应条件
1: dichloromethane; sulfuryl chloride 2: aqueous ammonia / 150 °C View Scheme
参考文献
I.G.Farbenind.
Patent: DE621710 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 299
反应条件
TEA in tetrahydrofuran
T=20°C; 1 h;
参考文献
Chilin, Adriana; Marzaro, Giovanni; Zanatta, Samuele; Barbieri, Vera; Pastorini, Giovanni; Manzini, Paolo; Guiotto, Adriano
Tetrahedron, 2006 , vol. 62, # 52 p. 12351 - 12356
反应条件
in tetrahydrofuran
T=20°C; 8 h; Inert atmosphere;
参考文献
Yang, Haoran; Huang, Danfeng; Wang, Ke-Hu; Xu, Changming; Niu, Teng; Hu, Yulai
Tetrahedron, 2013 , vol. 69, # 12 p. 2588 - 2593
反应条件
1: carbon dioxide; 4-methoxy-aniline With 2-pyrrolidone electrogenerated base*Et4N(+) in acetonitrile
T=20°C; Carboxylation; 1 h;
2: ethyl iodide in acetonitrile
T=20°C; Esterification;
参考文献
Feroci, Marta; Inesi, Achille; Rossi, Leucio
Tetrahedron Letters, 2000 , vol. 41, # 6 p. 963 - 966
反应条件
triethylamine; palladium dichloride in N,N-dimethyl acetamide
T=70°C; P=760.051 Torr; 24 h; Schlenk technique;
参考文献
Ren, Long; Jiao, Ning
Chemical Communications, 2014 , vol. 50, # 28 p. 3706 - 3709
