(4-乙酰氧基-2,3,6-三甲基-苯基)乙酸酯合成路线 （共 23 条）
反应条件
1: 2,3,5-trimethyl hydroquinone; C22H44O2 With pyridine
T=165 - 175°C; 6 h; Inert atmosphere;
2: acetic anhydride With pyridine
T=0 - 20°C; Inert atmosphere;
参考文献
Gembus, Vincent; Sala-Jung, Nathalie; Uguen, Daniel
Bulletin of the Chemical Society of Japan, 2009 , vol. 82, # 7 p. 843 - 854
反应条件
in toluene
4 h; Heating / reflux; Product distribution / selectivity;
参考文献
Galileo Pharmaceuticals, Inc.
Patent: US2006/128790 A1, 2006 ;
Location in patent: Page/Page column 70 ;
反应条件
sulfuric acid
T=30 - 50°C; 3 h;
参考文献
Degussa AG
Patent: US6350897 B2, 2002 ;
Location in patent: Example 2-3 ;
反应条件
boron trifluoride dimethyl etherate
参考文献
Budzikiewicz et al.
Monatshefte fuer Chemie, 1959 , vol. 90, p. 609,619
反应条件
1: CHCl3; lead (IV)-acetate
2: dimethyl ether BF3
View Scheme
参考文献
Budzikiewicz et al.
Monatshefte fuer Chemie, 1959 , vol. 90, p. 609,619
反应条件
boron trifluoride dimethyl etherate
参考文献
Budzikiewicz,H.; Gunawan,J.
Monatshefte fuer Chemie, 1973 , vol. 104, p. 876 - 884
反应条件
sulfuric acid
T=50°C; 0.5 h; effect of catalysts; MechanismThermodynamic data;
参考文献
Kharchuk, V. G.; Kolenko, I. P.
J. Gen. Chem. USSR (Engl. Transl.), 1987 , vol. 57, # 4 p. 923 - 930,819 - 826
反应条件
peracetic acid
T=50°C; 0.25 h; Product distributionKineticsThermodynamic data;
参考文献
Kharchuk, V. G.; Kolenko, I. P.; Petrov, L. A.; Gus'kova, L. M.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 11 p. 2071 - 2078
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 11 p. 2306 - 2315
反应条件
peracetic acid
T=50°C; 0.25 h; Product distributionKineticsThermodynamic data;
参考文献
Kharchuk, V. G.; Kolenko, I. P.; Petrov, L. A.; Gus'kova, L. M.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 11 p. 2071 - 2078
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 11 p. 2306 - 2315
参考文献
Degussa AG
Patent: US6350897 B2, 2002 ;
Location in patent: Page column 4-5 ;
