1: EtCOSEt With lithium diisopropyl amide in dichloromethane T=-78°C; 0.25 h; 2: chloro-trimethyl-silane in tetrahydrofuran T=-78 - 20°C; 2 h; Title compound not separated from byproducts;
参考文献
DeRoy, Patrick L.; Charette, Andre B.
Organic Letters, 2003 , vol. 5, # 22 p. 4163 - 4165
1: hex-5-ynoic acid With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.75 h; Inert atmosphere; 2: chloro-trimethyl-silane in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere; 3: With water; acetic acid in tetrahydrofuran; hexane 0.333333 h;
参考文献
Trost, Barry M.; Lehr, Konrad; Michaelis, David J.; Xu, Jiayi; Buckl, Andreas K.
Journal of the American Chemical Society, 2010 , vol. 132, # 26 p. 8915 - 8917
1: vinyl-magnesium bromide With N,N'-dimethyl-N,N'-propyleneurea; copper(I) bromide dimethylsulfide complex in tetrahydrofuran T=-40°C; 0.25 h; 2: chloro-trimethyl-silane; 2-ethyl-cyclopent-2-enone in tetrahydrofuran T=-40 - -20°C; 1 h; 3: With triethylamine in tetrahydrofuran T=-20 - 20°C;
参考文献
Saraber, Florence C. E.; Baranovsky, Alexander; Jansen, Ben J. M.; Posthumus, Maarten A.; De Groot, Aede
Tetrahedron, 2006 , vol. 62, # 8 p. 1726 - 1742
