2,2,2-三氟乙醇合成路线 （共 1089 条）
反应条件
sodium perchlorate; water T=70°C; Product distribution;
参考文献
Richard, John P.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1383 - 1396
反应条件
triethylamine in water T=65°C; homopropargyl rearrangement, var. of solvent, temp., ΔH(excit.); KineticsProduct distributionThermodynamic data;
参考文献
Chemische Berichte, , vol. 115, # 10 p. 3402 - 3413
参考文献
McBee et al.
Journal of the American Chemical Society, 1955 , vol. 77, p. 3149
参考文献
Bentley, T. William; Jones, Robert O; Kang, Dae Ho; Koo, Sun
Journal of Physical Organic Chemistry, 2009 , vol. 22, # 9 p. 799 - 806
反应条件
phosphorus pentachloride T=20°C; 12 h;
参考文献
Timperley, Christopher M.; Holden, Ian; Morton, Ian J.; Waters, Matthew J.
Journal of Fluorine Chemistry, 2000 , vol. 106, # 2 p. 153 - 161
反应条件
triethylamine in diethyl ether T=20°C; Esterification; 12 h;
参考文献
Timperley, Christopher M.; Bird, Michael; Broderick, John F.; Holden, Ian; Morton, Ian J.; Waters, Matthew J.
Journal of Fluorine Chemistry, 2000 , vol. 104, # 2 p. 215 - 223
反应条件
trichlorophosphate; calcium chloride 3.5 h; Heating;
参考文献
Goryunov, E. I.; Petrovskii, P. V.; Shcherbina, T. M.; Laretina, A. P.; Zakharov, L. S.; Kabachnik, M. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990 , vol. 39, # 4.2 p. 787 - 794
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990 , # 4 p. 878 - 886
反应条件
in water T=20 - 24°C; solvolysis;
参考文献
Richard, John P.; Rothenberg, Marc E.; Jencks, William P.
Journal of the American Chemical Society, 1984 , vol. 106, # 5 p. 1361 - 1372
反应条件
sodium trifluoroethoxide 96 h; Heating;
参考文献
Foehlisch, Baldur; Gehrlach, Eberhard; Henle, Gerhard; Boberlin, Ursula; Herter, Rolf
Journal of Chemical Research, Miniprint, 1991 , p. 1462 - 1492
反应条件
1: 2,2,2-trifluoroethanol With sodium hydride in tetrahydrofuran T=20°C; 0.5 h; 2: (4-methoxyphenyl)phosphothioic dichloride in tetrahydrofuran T=20°C; Further stages.;
参考文献
Sawa, Masaaki; Tsukamoto, Takako; Kiyoi, Takao; Kurokawa, Kiriko; Nakajima, Fumio; Nakada, Yuichiro; Yokota, Koichi; Inoue, Yoshimasa; Kondo, Hirosato; Yoshino, Kohichiro
Journal of Medicinal Chemistry, 2002 , vol. 45, # 4 p. 930 - 936
