L-苯丙氨酸甲酯盐酸盐合成路线 （共 169 条）
反应条件
Multistep reaction.;
参考文献
Harned, Andrew M; Mukherjee, Shubhasish; Flynn, Daniel L; Hanson, Paul R
Organic letters, 2003 , vol. 5, # 1 p. 15 - 18
反应条件
sodium carbonate in water; ethyl acetate T=0 - 16°C;
参考文献
Sun, Dequn; Zhang, Lingzi; Wang, Jin
Asian Journal of Chemistry, 2012 , vol. 24, # 1 p. 319 - 322
反应条件
hydrogenchloride; sodium hydrogencarbonate
参考文献
INSTITUT NATIONAL POLYTECHNIQUE DE LORRAINE
Patent: US2012/97884 A1, 2012 ;
反应条件
1: 1,4-dioxane 2: triethylamine View Scheme
参考文献
Mandadapu, Sivakoteswara Rao; Gunnam, Mallikarjuna Reddy; Tiew, Kok-Chuan; Uy, Roxanne Adeline Z.; Prior, Allan M.; Alliston, Kevin R.; Hua, Duy H.; Kim, Yunjeong; Chang, Kyeong-Ok; Groutas, William C.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 62 - 65
反应条件
1: 60 percent / CaCl2, thermolysin / dimethylformamide; various solvent(s) / 24 h / 38 °C / pH 7.0 2: 74 percent / 1 M NaOH / dioxane / 3 h / Ambient temperature 3: 64 percent / α-chymotrypsin / dimethylformamide; various solvent(s) / 20 h / 38 °C / pH 7 4: 59 percent / ferric chloride / dimethylformamide; H2O / 0.5 h / 35 °C 5: 1.) Na/NH3, 2.) NH4Cl, 3.) trifluoroacetic acid, O2 View Scheme
参考文献
Cerovsky, Vaclav
Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 6 p. 1352 - 1360
反应条件
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h;
参考文献
Michel Brunel, Jean; Salmi, Chanaz; Letourneux, Yves
Tetrahedron Letters, 2005 , vol. 46, # 2 p. 217 - 220
反应条件
triethylamine in toluene T=-14°C; 1 h;
参考文献
Joshi, Kiran; Bao, Jiang; Goldman, Alan S.; Kohn, Joachim
Journal of the American Chemical Society, 1992 , vol. 114, # 17 p. 6649 - 6652
反应条件
bislt;lt;4-(2,2-dimethyl-1,3-dioxolyl)methylgt;carbodiimide; triethylamine in N,N-dimethyl-formamide 24 h; Ambient temperature;
参考文献
Gibson, Frank S.; Park, Myung Sook; Rapoport, Henry
Journal of Organic Chemistry, 1994 , vol. 59, # 24 p. 7503 - 7507
反应条件
4-methyl-morpholine; N-(4,6-dimethoxy-1,3,5-triazin-2-yl)strychninium tetrafluoroborate; [3H]-Strychnine in chloroform T=0 - 20°C;
参考文献
Kolesinska, Beata; Kasperowicz, Katarzyna; Sochacki, Marek; Mazur, Adam; Jankowski, Stefan; Kaminski, Zbigniew J.
Tetrahedron Letters, 2010 , vol. 51, # 1 p. 20 - 22
反应条件
4-methyl-morpholine in N,N-dimethyl-formamide
参考文献
Kawasaki; Tsuji; Hirase; Miyano; Imoto; Iwamoto
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 3 p. 584 - 589
