1-[7-甲氧基-6-(2-哌啶-1-基乙氧基)-4-丙-2-基氧基-1-苯并呋喃-5-基]-3-甲基脲合成路线 （共 6 条）
反应条件
in toluene
5 h; Ambient temperature;
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 65 percent / K2CO3 / acetonitrile / 8 h / Heating
2: 90 percent / 2 N HCl / 5 h / Heating
3: 64 percent / toluene / 5 h / Ambient temperature
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 50 percent / aq. AcOH, HCl(g) / 0.5 h / 90 °C
2: 65 percent / K2CO3 / acetonitrile / 8 h / Heating
3: 90 percent / 2 N HCl / 5 h / Heating
4: 64 percent / toluene / 5 h / Ambient temperature
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 65 percent / K2CO3 / acetonitrile / 8 h / Heating
2: 90 percent / 2 N HCl / 5 h / Heating
3: 64 percent / toluene / 5 h / Ambient temperature
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 47 percent / KOH / H2O / 1 h / Heating
2: 50 percent / aq. AcOH, HCl(g) / 0.5 h / 90 °C
3: 65 percent / K2CO3 / acetonitrile / 8 h / Heating
4: 90 percent / 2 N HCl / 5 h / Heating
5: 64 percent / toluene / 5 h / Ambient temperature
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
反应条件
1: 90 percent / 2 N HCl / 5 h / Heating
2: 64 percent / toluene / 5 h / Ambient temperature
View Scheme
参考文献
Bourgery, Guy; Dostert, Philippe; Lacour, Alain; Langlois, Michel; Pourrias, Bernard; Tisne-Versailles, Jacky
Journal of Medicinal Chemistry, 1981 , vol. 24, # 2 p. 159 - 167
