5-羟基-2-甲基吲哚-3-羧酸乙酯合成路线 （共 11 条）
反应条件
zinc(II) iodide in dichloromethane Nenitzescu reaction; 0.666667 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 43, # 4 p. 873 - 879
反应条件
acetic acid T=15 - 40°C; Nenitzescu indole synthesis; 2.5 h;
参考文献
Research on Chemical Intermediates, , vol. 36, # 8 p. 975 - 983
反应条件
1: methanol 2: dioxane / Heating View Scheme
参考文献
Augelli-Szafran, Corinne E.; Jaen, Juan C.; Moreland, David W.; Nelson, Carrie B.; Penvose-Yi, Jan R.; Schwarz, Roy D.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 15 p. 1991 - 1996
反应条件
1: With water; sodium hydroxide in tetrahydrofuran 48 h; Reflux; 2: With hydrogenchloride in water pH=2;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 13 p. 3855 - 3868
反应条件
bromine in acetic acid
参考文献
Hiremath, Shivayogi P.; Badami, Prema S.; Purohit, Muralidhar G.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 5 p. 437 - 440
反应条件
20 percent aq. HCl 2.5 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 14 p. 3094 - 3102
参考文献
Nenitzescu
Bulet. Soc. chim. Romania, vol. 11, p. 37
Chem. Zentralbl., 1929 , vol. 100, # II p. 2332
反应条件
Fremy’s salt; acetic acid; acetone
Reagens 4: KH2PO4;
参考文献
Teuber; Thaler
Chemische Berichte, 1958 , vol. 91, p. 2253,2269
参考文献
Teuber; Thaler
Chemische Berichte, 1958 , vol. 91, p. 2253,2269
反应条件
potassium carbonate in acetone
1.) reflux, 4 h, 2.) 25 deg C, 48 h;
参考文献
Parr, Rodney W.; Reiss, James A.
Australian Journal of Chemistry, 1984 , vol. 37, # 6 p. 1263 - 1270
