3-甲基-3-丁烯-1-醇合成路线 （共 220 条）
反应条件
copper; zinc in diethyl ether Heating;
参考文献
Perraud,R.; Arnaud,P.
Bulletin de la Societe Chimique de France, 1968 , p. 1540 - 1542
反应条件
1: 93 percent / PTSA / 1 h / 0 °C 2: K3Fe(CN)6; K2CO3; OsO4 / (DHQD)2-PHAL / 2-methyl-propan-2-ol; H2O / 24 h / 0 °C 3: 96 percent / pyridine / 18 h / 20 °C 4: ethanol; H2O / 18 h / 20 °C 5: 3N aq. NaOH / 3 h / 70 °C 6: HCl; PTSA / methanol; acetone / 8 h / 20 °C / pH 2 View Scheme
参考文献
Fernandes, Rodney A.; Kumar, Pradeep
Tetrahedron Asymmetry, 1999 , vol. 10, # 22 p. 4349 - 4356
反应条件
1: [Ru(COD)(Cl2)]2; 1-n-butyl-3-methylimidazolium chloride; potassium tert-butylate; tri-cyclo-hexyl-phosphine / toluene / 12 h / |Reflux; |Inert atmosphere; |Schlenk technique 2: dcype; [Ru(Pn-Bu3)4H2] / toluene / 12 h / |Reflux; |Inert atmosphere; |Schlenk technique View Scheme
反应条件
1: 1) aq. HNO3, 2) NaNO2 / 1) 20 deg C, 4 h, 2) 50-60 deg C, 4 h 2: 76 percent / p-TsOH / 1 h / 100 - 110 °C View Scheme
参考文献
Sargsyan, M. S.; Mkrtumyan, S. A.; Avakyan, O. V.; Manukyan, A. T.; Gevorkyan, A. A.
Chemistry of Natural Compounds, 1991 , vol. 27, # 3 p. 270 - 271
Khimiya Prirodnykh Soedinenii, 1990 , # 3 p. 313 - 314
反应条件
thionyl chloride in pyridine a) 0 deg C, 6 h, b) RT, overnight;
参考文献
Journal of Organic Chemistry, , vol. 52, # 8 p. 1437 - 1439
反应条件
molecular sieve; pyridinium chlorochromate in dichloromethane T=20°C; 4 h;
参考文献
Tetrahedron Letters, , vol. 44, # 6 p. 1275 - 1278
反应条件
oxygen; 3.8percent by weight of Pd, 3.1percent by weight of Au on carbon in o-xylene T=80°C; P=3750.38 Torr; 1 h; Autoclave; Product distribution / selectivity;
参考文献
US2011/4025 A1, ;
Page/Page column 3 ;
反应条件
[Ru(COD)(Cl2)]2; potassium tert-butylate; 1-n-butyl-3-methylimidazolium chloride; tri-cyclo-hexyl-phosphine in toluene 12 h; RefluxInert atmosphereSchlenk technique;
参考文献
EP2597081 A1, ;
Paragraph 0124 ;
反应条件
[Ru(PnOct3)4(H)2] T=120°C; 20 h; RefluxInert atmosphereSchlenk technique;
参考文献
EP2597081 A1, ;
Paragraph 0124 ;
反应条件
oxygen; ethylenediamine-complexed silver oxalate solution on steatite calcined in air Product distribution / selectivity;
参考文献
US2011/15446 A1, ;
Page/Page column 3-4 ;
