1-(三苯基甲基)-2-氮丙啶羧酸甲酯合成路线 （共 11 条）
反应条件
sulfuryl dichloride; triethylamine in toluene -50 deg C, 1 h, 23 deg C, 16 h;
参考文献
Molander, Gary A.; Stengel, Peter J.
Tetrahedron, 1997 , vol. 53, # 26 p. 8887 - 8912
反应条件
triethylamine in dichloromethane
参考文献
Bayer Schering Pharma Aktiengesellschaft
Patent: EP1944288 A1, 2008 ;
反应条件
sodium hydride in tetrahydrofuran T=25°C; 24 h;
参考文献
Organic Letters, , vol. 9, # 17 p. 3295 - 3298
反应条件
triethylamine in acetone 12 h;
参考文献
Shtrumfs; Hermane; Kalvinsh; Trapencieris
Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 2 p. 169 - 174
反应条件
potassium fluoride in acetonitrile Heating; Yield given;
参考文献
Journal of Fluorine Chemistry, , vol. 16, p. 183 - 188
反应条件
1: triethylamine / dichloromethane / 18 h / 0 °C / Inert atmosphere 2: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere 3: triethylamine / ethylene glycol dimethyl ether / 72 h / 80 °C / Inert atmosphere View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4815 - 4830
反应条件
chloroform Behandeln mit Tritylchlorid und Methansulfonylchlorid und Erwaermen des Reaktionsgemisches unter Zusatz von Methanol;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 22, p. 262,271
反应条件
diisobutylaluminium hydride in tetrahydrofuran T=23°C; 23 h;
参考文献
Molander, Gary A.; Stengel, Peter J.
Tetrahedron, 1997 , vol. 53, # 26 p. 8887 - 8912
反应条件
methanol; trifluoroacetic acid in dichloromethane T=0°C; Inert atmosphere;
参考文献
King, Amber M.; Salome, Christophe; Dinsmore, Jason; Salome-Grosjean, Elise; De Ryck, Marc; Kaminski, Rafal; Valade, Anne; Kohn, Harold
Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4815 - 4830
反应条件
anhydrous sodium hydrogen carbonate; trifluoroacetic acid in diethyl ether; chloroform; water
