反应条件
1: 1.) t-BuLi, 3.) 0.2 M HCl / 1.) THF, pentane, -65 deg C to 0 deg C, 15 min, 2.) -65 deg C to room temperature, 14 h, 3.) acetone, H2O, 1 h 2: 14 percent / 1,1,1,3,3,3-hexamethyldisilazane, BuLi / tetrahydrofuran; hexane / 1.) 0 deg C, 20 min, 2.) -78 deg C, 15 min, 3.) -78 deg C, 1 h 3: 81 percent / DIBAL / toluene; CH2Cl2 / 1.5 h View Scheme
参考文献
Fujiwara, Tooru; Sawabe, Koichi; Takeda, Takeshi
Tetrahedron, 1997 , vol. 53, # 25 p. 8349 - 8370
