反应条件
1: 1-(tert-butoxy-carbonyl)piperidine With sec.-butyllithium; (+)-sparteine surrogate in hexanes; diethyl ether T=-78°C; 6 h; Inert atmosphere; 2: dimethyl(phenyl)silyl chloride in hexanes; diethyl ether T=-78 - 40°C; Inert atmosphere; 3: methyl chloroformate in hexanes; diethyl ether T=-40 - 20°C; Inert atmosphere; optical yield given as percent ee;
参考文献
Stead, Darren; Carbone, Giorgio; O'Brien, Peter; Campos, Kevin R.; Coldham, Iain; Sanderson, Adam
Journal of the American Chemical Society, 2010 , vol. 132, # 21 p. 7260 - 7261
