(S)-甲基-2-溴-3-羟基丙酸甲酯合成路线 （共 8 条）
反应条件
hydrogen bromide in water T=65°C; 21 h;
参考文献
The University of Akron; Pugh, Coleen R.; Singh, Anirudha
Patent: US8524942 B2, 2013 ;
Location in patent: Page/Page column 17 ;
反应条件
1: (L)-serine With bromic acid; potassium bromide; sodium nitrite in water T=-10 - 20°C; 2: methanol With bromic acid in water T=65°C; 48 h;
参考文献
YUHAN CORPORATION; HUR, Youn; KIM, Dong-Hyun; KIM, Eun-Kyung; PARK, Jin-Hwi; JOO, Jae-Eun; KANG, Ho-Woong; OH, Se-Woong; KIM, Dong-Kyun; AHN, Kyoung-Kyu
Patent: WO2013/43001 A1, 2013 ;
Location in patent: Paragraph 1496; 1497; 1498 ;
反应条件
dibromamine-T in water; acetonitrile T=20°C; 0.166667 h;
参考文献
Phukan, Prodeep; Chakraborty, Pranita; Kataki, Dolly
Journal of Organic Chemistry, 2006 , vol. 71, # 20 p. 7533 - 7537
反应条件
hydrogen bromide in methanol; dichloromethane
反应条件
bromine; silver nitrate in water
参考文献
Journal of Organic Chemistry, , vol. 32, p. 244 - 246
反应条件
bromine in water T=30°C; other temperatures (22, 38, 46, 54 deg C), ΔH*, ΔS*, ΔG*; Rate constantThermodynamic dataProduct distribution;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 57, # 5 p. 1394 - 1400
反应条件
water; bromine; silver nitrate 9 h; Inert atmosphereCooling with ice;
参考文献
Synlett, , # 13 p. 1947 - 1950
