1,3-二溴-5,5-二甲基海因合成路线 （共 64 条）
反应条件
1: pyrene; 1,3-dibromo-5,5-dimethyl-hydantoin in dichloromethane
T=20°C; 1 h;
2: 4,4'-dimethyldiphenylamine With tri-tert-butyl phosphine; palladium diacetate; caesium carbonate in o-xylene
T=120°C; Buchwald-Hartwig Coupling; 48 h; Overall yield = 73 percent;
参考文献
Hu, Jian-Yong; Feng, Xing; Seto, Nobuyuki; Do, Jung-Hee; Zeng, Xi; Tao, Zhu; Yamato, Takehiko
Journal of Molecular Structure, 2013 , vol. 1035, p. 19 - 26
反应条件
acetic acid in C6H5Cl
参考文献
Massachusetts Institute of Technology
Patent: US7399639 B2, 2008 ;
参考文献
Teva Pharmaceutical Industries, Ltd.
Patent: US4851426 A1, 1989 ;
反应条件
tetrachloromethane; dibenzoyl peroxide
参考文献
Pintado
Rev. Fac. Cienc. quim. Univ. La Plata, 1955 , vol. 29, p. 53,56
参考文献
Bonafede
Rev. Fac. Cienc. quim. Univ. La Plata, 1956 , vol. 29, p. 41,44
反应条件
tetrachloromethane; dibenzoyl peroxide
T=80 - 85°C; Irradiation.Wolfram-Lampe;
参考文献
Orazi; Giunti
Anales de la Asociacion Quimica Argentina (1921-2001), 1951 , vol. 39, p. 84,89
反应条件
tetrachloromethane
Irradiation;
参考文献
Jeandupeux
Rev.Fac.Cienc.quim.Univ.La Plata, 1959 , vol. 32, p. 75,77,82,83
反应条件
tetrachloromethane; dibenzoyl peroxide
参考文献
Bonafede
Rev. Fac. Cienc. quim. Univ. La Plata, 1955 , vol. 29, p. 41,45, 47
反应条件
tetrachloromethane
Irradiation;
参考文献
Orazi; Giunti
Anales de la Asociacion Quimica Argentina (1921-2001), 1951 , vol. 39, p. 84,89
反应条件
dibenzoyl peroxide in tetrachloromethane
参考文献
American Home Products Corporation
Patent: US5104892 A1, 1992 ;
