toluene-4-sulfonic acid in acetone Ambient temperature;
参考文献
Watanabe, K. A.; Matsuda, A.; Halat, M. J.; Hollenberg, D. H.; Nisselbaum, J. S.; Fox, J. J.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 7 p. 893 - 897
1: (S)-(-)-N-(2-Ethyl-6-methyl-phenyl)-alanin With sodium tetrahydroborate; sulfuric acid in tetrahydrofuran T=20°C; 2: chloroacetyl chloride With sodium carbonate in benzene T=20°C; 3 h; 3: 2,2-dimethoxy-propane With toluene-4-sulfonic acid in methanol 36 h; Heating; Title compound not separated from byproducts;
参考文献
Zheng, Liangyu; Zhang, Suoqin; Wang, Fang; Gao, Gui; Cao, Shugui
Canadian Journal of Chemistry, 2006 , vol. 84, # 8 p. 1058 - 1063