1,1,1-三(羟甲基)乙烷合成路线 （共 76 条）
反应条件
1.1: CaCl2; HCl / dioxane / 10 h / Heating
2.1: Na / xylene / 2 h / Heating
2.2: 110 g / 15-crown-5 / xylene; dioxane
3.1: aq. H2SO4 / 10 h / Heating
4.1: 41 g / EtOH / Heating
View Scheme
参考文献
Kaspar; Hamplova; Novotna; Studenovsky; Ilavsky
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 2002 , vol. 392, p. 17 - 30
反应条件
1: 64 percent / ethyl carbonate, KOH / ethanol / 0.25 h / Heating
2: 99 percent / pyridine / CH2Cl2
3: 10 percent / BF3*Et2O / CH2Cl2 / 24 h / Ambient temperature
View Scheme
参考文献
Rakus, Klaus; Verevkin, Sergey P.; Peng, Wei-Hong; Beckhaus, Hans-Dieter; Ruechardt, Christoph
Liebigs Annalen, 1995 , # 12 p. 2059 - 2068
反应条件
phosphorus tribromide in acetonitrile
24.5 h; Heating;
参考文献
Cheng, Chien-Chung; Huang, Yan-Chen; Liu, Ming-Chan
Journal of the Chinese Chemical Society, 2004 , vol. 51, # 5 B p. 1201 - 1208
反应条件
toluene-4-sulfonic acid in tetrahydrofuran
T=20°C; 16 h;
参考文献
Dyke, Jason Christopher; Knight, Kelly Jane; Zhou, Huaxing; Chiu, Chi-Kai; Ko, Ching-Chang; You, Wei
Journal of Materials Chemistry, 2012 , vol. 22, # 43 p. 22888 - 22898
反应条件
1: 1,1,1-tris(hydroxymethyl)-ethane With toluene-4-sulfonic acid in tetrahydrofuran
T=20°C; 2 h;
2: benzaldehyde dimethyl acetal in tetrahydrofuran
T=20°C; 18 h; Further stages.;
参考文献
Glauser, Thierry; Stancik, Cheryl M.; Moeller, Michael; Voytek, Sarah; Gast, Alice P.; Hedrick, James L.
Macromolecules, 2002 , vol. 35, # 15 p. 5774 - 5781
参考文献
Koch; Zerner
Monatshefte fuer Chemie, 1901 , vol. 22, p. 456
