2,2,3,3-四甲基环丙烷羧酸乙酯合成路线 （共 6 条）
反应条件
potassium hydroxide in methanol Heating;
参考文献
Thamattoor, Dasan M.; Snoonian, John R.; Sulzbach, Horst M.; Hadad, Christopher M.
Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 5886 - 5895
反应条件
methyltrioxorhenium (VII)
T=50 - 60°C; 72 h;
参考文献
Zhu, Zuolin; Espenson, James H.
Journal of the American Chemical Society, 1996 , vol. 118, # 41 p. 9901 - 9907
反应条件
sulfuric acid
Heating / reflux;
参考文献
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
Patent: WO2008/102348 A1, 2008 ;
Location in patent: Page/Page column 39 ;
参考文献
Pfizer Inc.
Patent: US4454328 A1, 1984 ;
反应条件
1: KOH / methanol / 3 h / Heating
2: 0.702 g / tetrahydrofuran; diethyl ether / 2 h / -5 °C
View Scheme
参考文献
Thamattoor, Dasan M.; Snoonian, John R.; Sulzbach, Horst M.; Hadad, Christopher M.
Journal of Organic Chemistry, 1999 , vol. 64, # 16 p. 5886 - 5895
反应条件
(i) aq. LiOH, EtOH, (ii) /BRN= 3587162/, Et2O; Multistep reaction;
参考文献
Meshcheryakov,A.P.; Dolgii,I.E.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1961 , p. 458 - 462
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1961 , # 3 p. 496 - 501
