4-苯基-1,3-二氧杂环乙烷合成路线 （共 34 条）
反应条件
zinc(II) chloride T=70°C; 0.05 h; other time, temperature; Product distribution;
参考文献
J. Appl. Chem. USSR (Engl. Transl.), , vol. 55, # 11 p. 2538 - 2542,2295 - 2298
反应条件
1: 83 percent / aq. HCl / 20 h / 80 °C 2: 54 percent / KOH / diethyl ether; methanol / 3 h 3: 70 percent / pyridine / CH2Cl2 4: 77 percent / hydrazine hydrate / CH2Cl2 / 2 h 5: 60 percent / Na2SO4 / CH2Cl2 / 2 h 6: CH2Cl2 / 48 h 7: 26 percent / benzene; various solvent(s) / 72 h / 110 °C View Scheme
参考文献
Merkley, Nadine; Warkentin, John
Canadian Journal of Chemistry, 2002 , vol. 80, # 9 p. 1187 - 1195
反应条件
1: With sulfuric acid; 2-hydroxy-2-methyl-propionitrile in hexane 2 h; Heating; 2: Alkaline hydrolysis;
参考文献
Kuznetsov; Brusilovskii
Chemistry of Heterocyclic Compounds, 2001 , vol. 37, # 5 p. 574 - 575
反应条件
sulfuric acid in hexane 2 h; Heating; Title compound not separated from byproducts;
参考文献
Kuznetsov; Brusilovskii
Chemistry of Heterocyclic Compounds, 2001 , vol. 37, # 5 p. 574 - 575
反应条件
1: With sulfuric acid; 2-hydroxy-2-methyl-propionitrile in hexane 2 h; Heating; 2: Alkaline hydrolysis;
参考文献
Kuznetsov; Brusilovskii
Chemistry of Heterocyclic Compounds, 2001 , vol. 37, # 5 p. 574 - 575
反应条件
sulfuric acid in hexane 2 h; Heating; Title compound not separated from byproducts;
参考文献
Kuznetsov; Brusilovskii
Chemistry of Heterocyclic Compounds, 2001 , vol. 37, # 5 p. 574 - 575
反应条件
hydrogenchloride; ammonium chloride T=100°C;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 1 p. 290 - 295
反应条件
iodo trichloro silane
参考文献
Tetrahedron Letters, , vol. 33, # 12 p. 1657 - 1660
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride T=35 - 40°C; 30 h; Yield given;
参考文献
Safiev, O. G.; Nazarov, D. V.; Zorin, V. V.; Rakhmankulov, D. L.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 9 p. 1788 - 1789
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 9 p. 2022 - 2023
反应条件
zinc(II) chloride
T=70°C; 0.05 h; other time, temperature; Product distribution;
参考文献
Mironov, I. V.; Mel'nitskii, I. A.; Siareva, I. N.; Kiladze, T. K.; Kantor, E. A.; Rakhmankulov, D. L.
J. Appl. Chem. USSR (Engl. Transl.), 1982 , vol. 55, # 11 p. 2538 - 2542,2295 - 2298
