2,4,6-三甲基苯磺酰氯合成路线 （共 56 条）
反应条件
triethylamine in tert-butyl methyl ether T=0 - 10°C; 3.5 h; Inert atmosphereLarge scale reaction;
参考文献
Mendiola, Javier; Rincon, Juan A.; Mateos, Carlos; Soriano, Jose Francisco; De Frutos, Oscar; Niemeier, Jeffry K.; Davis, Edward M.
Organic Process Research and Development, 2009 , vol. 13, # 2 p. 263 - 267
反应条件
1: 1.) Et3N; 2.) DBN / 1.) CH2Cl2, in ice-bath, 30 min; 2.) benzene, reflux, 1 h 2: 1.) NBS, 1percent HClO4; 2.) AcONa / 2.) Raney-Ni / 1.) acetone, H2O, r. t., 30 min; 2.) MeOH, CH2Cl2, 30 min 3: 70 percent / H2 / Pd(OH)2/C / benzene; ethanol; cyclohexane / 2 h / Heating View Scheme
参考文献
Wiesner; Tsai; Sen; et al.
Helvetica Chimica Acta, 1983 , vol. 66, # 8 p. 2632 - 2640
反应条件
ammonium hydroxide in chloroform T=20°C; 2 h;
参考文献
Hayashi, Tamio; Kawai, Masahiro; Tokunaga, Norihito
Angewandte Chemie - International Edition, 2004 , vol. 43, # 45 p. 6125 - 6128
参考文献
THE NUTRASWEET COMPANY, (a Delaware corporation)
Patent: EP299533 A2, 1989 ;
反应条件
in acetonitrile 25°C, 1 h;
参考文献
Gmelin Handbook: F: PerFHalOrg.SVol.3, 6.2.2, page 1 - 48
反应条件
sodium azide in ethanol T=25°C; 0.2 h;
参考文献
Jafarpour, Maasoumeh; Rezaeifard, Abdolreza; Golshani, Tayebeh
Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 1 p. 140 - 148
反应条件
triethylamine in tetrahydrofuran T=20°C; 12 h; Cooling with ice;
参考文献
Li, Wenjun; Wu, Wenbin; Yu, Feng; Huang, Huicai; Liang, Xinmiao; Ye, Jinxing
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2505 - 2511
反应条件
sodium hydroxide; water in dichloromethane T=0°C; 1.33333 h; Product distribution / selectivity;
参考文献
Bosch, Boris Elmar; Gerhartz, Frank
Patent: US2005/59842 A1, 2005 ;
Location in patent: Page/Page column 5 ;
参考文献
Jafarpour, Maasoumeh; Rezaeifard, Abdolreza; Golshani, Tayebeh
Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 1 p. 140 - 148
反应条件
1: 100 percent / triethylamine / CH2Cl2 2: 95 percent / K2CO3 / acetonitrile / 7 h / Heating View Scheme
参考文献
Inoue, Tadashi; Liu, Ji-Feng; Buske, Dana C.; Abiko, Atsushi
Journal of Organic Chemistry, 2002 , vol. 67, # 15 p. 5250 - 5256
