773837-37-9合成路线 （共 596 条）
反应条件
sodium hydrogensulfite T=0 - 60°C;
参考文献
Dong, Jizhe; Gong, Yanchun; Liu, Jun; Chen, Xiangfeng; Wen, Xiaoan; Sun, Hongbin
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1383 - 1393
反应条件
1,4-diaza-bicyclo[2.2.2]octane in dimethyl sulfoxide T=20°C; 1 h;
参考文献
Payne, Linda S.; Tran, Lekhanh O.; Zhuang, Linghang H.; Young, Steven D.; Egbertson, Melissa S.; Wai, John S.; Embrey, Mark W.; Fisher, Thorsten E.; Guare, James P.; Langford, H. Marie; Melamed, Jeffrey Y.; Clark, David L.
Patent: US2003/229079 A1, 2003 ;
Location in patent: Page 40 ;
反应条件
1: heptanal With sodium hydrogensulfite in water 0.5 h; 2: sodium cyanide in water 0.25 h; 3: With sulfuric acid T=125°C; 3 h;
参考文献
UNIVERSITE DE GENEVE; Moeller, Michael; Asmus, Lutz; Gurny, Robert
Patent: US2013/131190 A1, 2013 ;
Location in patent: Paragraph 0077 ;
反应条件
copper (I) cyanide T=20°C;
参考文献
Habibi, Davood; Heydari, Somayyeh; Nasrollahzadeh, Mahmoud
2012 , vol. 36, # 10 p. 573 - 574,2
反应条件
1: methanesulfonyl chloride; 3-hydroxyazetidine-1-carboxylic acid tert-butyl ester With triethylamine in ethyl acetate T=0°C; 1 h; 2: sodium cyanide in dimethyl sulfoxide T=130°C; 48 h;
参考文献
Okamoto, Osamu; Falgueyret, Jean-Pierre; Oballa, Renata Marcella; Prasit, Petpiboon; Rydzewski, Robert
Patent: US2003/229226 A1, 2003 ;
Location in patent: Page 20 ;
反应条件
in dimethyl sulfoxide T=100 - 105°C; 100 h;
参考文献
PFIZER LIMITED; ACIRO, Caroline; BAGAL, Sharanjeet Kaur; HARVEY, John Wilson; JONES, Lyn Howard; MOWBRAY, Charles Eric; OWEN, Robert McKenzie; SABNIS, Yogesh Anil; STORER, Robert Ian; YEAP, Siew Kuen
Patent: WO2010/131145 A1, 2010 ;
Location in patent: Page/Page column 85-86 ;
反应条件
CuO in N,N-dimethyl-formamide T=100°C;
参考文献
Yapuri, Umanadh; Palle, Sadanandam; Gudaparthi, Omprakash; Narahari, Srinivasa Reddy; Rawat, Dhwajbahadur K.; Mukkanti, Khagga; Vantikommu, Jyothi
Tetrahedron Letters, 2013 , vol. 54, # 35 p. 4732 - 4734
反应条件
tri-tert-butyl phosphine; Pd2(dba)5; zinc in tetrahydrofuran; acetonitrile T=70°C; 2 h;
参考文献
Ushkov, Alexander V.; Grushin, Vladimir V.
Journal of the American Chemical Society, 2011 , vol. 133, # 28 p. 10999 - 11005
反应条件
sodium iodide in acetone 12 h; Reflux;
参考文献
Kim, Joong-Gon; Song, Young-Kyu; Jo, Ye-Hyun; Yu, Mi-Ran; Ju, Hyunwoo; Choi, Inho; Chung, Chan-Moon
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 4 p. 1131 - 1132
反应条件
sodium iodide in acetone 12 h; Reflux;
参考文献
Kim, Joong-Gon; Song, Young-Kyu; Jo, Ye-Hyun; Yu, Mi-Ran; Ju, Hyunwoo; Choi, Inho; Chung, Chan-Moon
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 4 p. 1131 - 1132
