773837-37-9合成路线 （共 596 条）
反应条件
sodium tetrahydroborate in methanol; formamide
参考文献
Kwon, Tae Hoon; Yoon, Ik Hwan; Shin, Ji-Sun; Lee, Young Hun; Kwon, Bong Jin; Lee, Kyung-Tae; Lee, Yong Sup
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2571 - 2574
反应条件
sodium tetrahydroborate in methanol; formamide
参考文献
Kwon, Tae Hoon; Yoon, Ik Hwan; Shin, Ji-Sun; Lee, Young Hun; Kwon, Bong Jin; Lee, Kyung-Tae; Lee, Yong Sup
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2571 - 2574
反应条件
ammonia; ammonium chloride in water T=0 - 20°C; 60 h;
参考文献
Guo, Di-Liang; Zhang, Xing-Jie; Wang, Rui-Rui; Zhou, Yu; Li, Zeng; Xu, Jin-Yi; Chen, Kai-Xian; Zheng, Yong-Tang; Liu, Hong
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 23 p. 7114 - 7118
反应条件
tri-tert-butyl phosphine; Pd2(dba)5; zinc in tetrahydrofuran; acetonitrile T=70°C; 2 h;
参考文献
Ushkov, Alexander V.; Grushin, Vladimir V.
Journal of the American Chemical Society, 2011 , vol. 133, # 28 p. 10999 - 11005
反应条件
1: ortho-anisaldehyde With DOWER(R)50WX4 in acetonitrile T=20°C; 0.0833333 h; 2: sodium cyanide in acetonitrile T=20°C; 2 h;
参考文献
Sofighaderi, Sargol; Setamdideh, Davood
Oriental Journal of Chemistry, 2013 , vol. 29, # 3 p. 1135 - 1137
反应条件
1: With ammonium chloride in methanol; water T=20°C; Strecker amino acid synthesis; 24.3333 h; 2: With hydrogenchloride; water 72 h; Reflux;
参考文献
Nieto, Sonia; Sayago, Francisco J.; Laborda, Pedro; Soler, Tatiana; Cativiela, Carlos; Urriolabeitia, Esteban P.
Tetrahedron, 2011 , vol. 67, # 23 p. 4185 - 4191
反应条件
C43H35F5N2OPd; oxygen; acetic acid in methanol; acetonitrile T=20°C; 1.5 h; Photolysis;
参考文献
Chow, Pui-Keong; To, Wai-Pong; Low, Kam-Hung; Che, Chi-Ming
Chemistry - An Asian Journal, 2014 , vol. 9, # 2 p. 534 - 545
反应条件
in 1,4-dioxane; water T=0 - 20°C; 16 h;
参考文献
APPLIED RESEARCH SYSTEMS ARS HOLDING N. V.
Patent: WO2004/98607 A1, 2004 ;
Location in patent: Page/Page column 52 ;
WO 2004/098607 A1
反应条件
in dimethyl sulfoxide T=90 - 98°C; 20 h;
参考文献
TAGWORKS PHARMACEUTICALS B.V.; ROBILLARD, Marc Stefan; VAN DUIJNHOVEN, Sander Martinus Johannes; POUDEROIJEN, Maarten Jozef; VERSTEEGEN, Ronny Mathieu
Patent: WO2014/81299 A1, 2014 ;
Location in patent: Page/Page column 119; 120 ;
反应条件
1: in dimethyl sulfoxide T=100°C; 4 h; 2: With iron(II) sulfate in water; dimethyl sulfoxide T=20°C; 8 h;
参考文献
ZAFGEN CORPORATION; CRAMP, Susan, Mary; DYKE, Hazel, Joan; PALLIN, Thomas, David; ZAHLER, Robert
Patent: WO2012/154676 A1, 2012 ;
Location in patent: Page/Page column 209 ;
WO 2012/154676 A1
