in methanol; water

oxygen; salcomine in N,N-dimethyl-formamide 72 h; Ambient temperature;

lithium aluminium tetrahydride in tetrahydrofuran; diethyl ether 1 h; Ambient temperature;

2: 95 percent / dimethylsulfoxide / 15 h / 80 °C 3: 86 percent / NaOH, 3N HCl / ethanol / 19 h / Heating 4: PCl5 / CH2Cl2 / 2 h / 25 °C 5: 44 percent / AlCl3 / 1,2-dichloro-ethane / 72 h / 20 °C 6: 79 percent / NaOH / methanol / 2 h / Ambient temperature 7: H2, 70percent HClO4 / 5percent Pd-C / 24 h / Ambient temperature 8: NaOH / methanol / 24 h / 5 °C View Scheme

1: 95 percent / dimethylsulfoxide / 15 h / 80 °C 2: 86 percent / NaOH, 3N HCl / ethanol / 19 h / Heating 3: PCl5 / CH2Cl2 / 2 h / 25 °C 4: 44 percent / AlCl3 / 1,2-dichloro-ethane / 72 h / 20 °C 5: 79 percent / NaOH / methanol / 2 h / Ambient temperature 6: H2, 70percent HClO4 / 5percent Pd-C / 24 h / Ambient temperature 7: NaOH / methanol / 24 h / 5 °C View Scheme

1: 1.) NaOH / p-TsOH / 1.) MeOH, reflux, 3 h; 2.) 60 degC, 2 h 2: PCl5 / CH2Cl2 / 2 h / 25 °C 3: 44 percent / AlCl3 / 1,2-dichloro-ethane / 72 h / 20 °C 4: 79 percent / NaOH / methanol / 2 h / Ambient temperature 5: H2, 70percent HClO4 / 5percent Pd-C / 24 h / Ambient temperature 6: NaOH / methanol / 24 h / 5 °C View Scheme

1: PCl5 / CH2Cl2 / 2 h / 25 °C 2: 44 percent / AlCl3 / 1,2-dichloro-ethane / 72 h / 20 °C 3: 79 percent / NaOH / methanol / 2 h / Ambient temperature 4: H2, 70percent HClO4 / 5percent Pd-C / 24 h / Ambient temperature 5: NaOH / methanol / 24 h / 5 °C View Scheme

1: 44 percent / AlCl3 / 1,2-dichloro-ethane / 72 h / 20 °C 2: 79 percent / NaOH / methanol / 2 h / Ambient temperature 3: H2, 70percent HClO4 / 5percent Pd-C / 24 h / Ambient temperature 4: NaOH / methanol / 24 h / 5 °C View Scheme

1: 86 percent / NaOH, 3N HCl / ethanol / 19 h / Heating 2: PCl5 / CH2Cl2 / 2 h / 25 °C 3: 44 percent / AlCl3 / 1,2-dichloro-ethane / 72 h / 20 °C 4: 79 percent / NaOH / methanol / 2 h / Ambient temperature 5: H2, 70percent HClO4 / 5percent Pd-C / 24 h / Ambient temperature 6: NaOH / methanol / 24 h / 5 °C View Scheme

sodium hydroxide in methanol T=5°C; 24 h; Yield given;