2-氯-4-甲氧基喹唑啉合成路线 （共 10 条）
参考文献
Wolf et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 4264
参考文献
Wolf et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 4264
参考文献
Lange et al.
Journal of the American Chemical Society, 1930 , vol. 52, p. 3696,3699
反应条件
methanol
T=20°C; 48 h;
参考文献
Almirall, S.A.; Eastwood, Paul Robert; Gonzalez Rodriguez, Jacob; Bach Taña, Jordi; Pages Santacana, Lluis Miquel; Taltavull Moll, Joan; Caturla Javaloyes, Juan Francisco
Patent: EP2338888 A1, 2011 ;
Location in patent: Paragraph 0167; 0169 ;
EP 2338888 A1
参考文献
Lange; Sheibley
Journal of the American Chemical Society, 1931 , vol. 53, p. 3867,3870
反应条件
1: trichlorophosphate / 16 h / 115 °C
2: methanol / 48 h / 20 °C
View Scheme
参考文献
ALMIRALL, S.A.; EASTWOOD, Paul Robert; GONZALEZ RODRIGUEZ, Jacob; BACH TANA, Jordi; PAGES SANTACANA, Lluis Miquel; TALTAVULL MOLL, Joan; CATURLA JAVALOYES, Juan Francisco; MATASSA, Victor Giulio
Patent: WO2011/76419 A1, 2011 ;
参考文献
Higashino
Yakugaku Zasshi, 1959 , vol. 79, p. 702
Chem.Abstr., 1959 , p. 21999
反应条件
phosphorus pentachloride; trichlorophosphate
参考文献
Higashino
Yakugaku Zasshi, 1959 , vol. 79, p. 702
Chem.Abstr., 1959 , p. 21999
参考文献
Higashino
Yakugaku Zasshi, 1959 , vol. 79, p. 702
Chem.Abstr., 1959 , p. 21999
反应条件
in toluene
4 h; Heating;
参考文献
Miki, Hideki; Kasahara, Fumiko
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 10 p. 3471 - 3475
