反应条件
aluminium trichloride; acetyl chloride in dichloromethane Friedel-Crafts acetylation; anhydrous AlCl3-powder in CH2Cl2 is stirred at 0°C under N2, addn. of acetylchloride in CH2Cl2, stirring (30 min), Cr-compd. is added dropwise within 30 min (stirring, 0°C), further stirring (room temp., 5 h); mixt. is poured into ice-water, sepn. of the layers, aq. layer is extd. with CH2Cl2, combined org. layers are washed (with water, aq. NaHCO3), dried (Na2SO4), concd. (vac., 40-50°C), chromy., main fraction (mixt. of Cr-compds.) is not separable;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 747 - 752
