二乙基[二氟(三甲基硅烷基)甲基]膦酸酯合成路线 （共 8 条）
反应条件
potassium fluoride T=20°C; 18 h;
参考文献
Journal of Fluorine Chemistry, , vol. 154, p. 43 - 46
反应条件
tetra-n-butylammonium difluorotriphenylsilicate(IV) in N,N-dimethyl-formamide T=-50 - 20°C; 15 h; Inert atmosphere;
参考文献
Alexandrova, Anastasia V.; Beier, Petr
Journal of Fluorine Chemistry, 2009 , vol. 130, # 5 p. 493 - 500
反应条件
1: With tetra-n-butylammonium difluorotriphenylsilicate(IV) in N,N-dimethyl-formamide T=-50 - 20°C; 15 h; Inert atmosphere; 2: With water in N,N-dimethyl-formamide T=20°C; 2 h; Inert atmosphere;
参考文献
Alexandrova, Anastasia V.; Beier, Petr
Journal of Fluorine Chemistry, 2009 , vol. 130, # 5 p. 493 - 500
反应条件
n-butyllithium in tetrahydrofuran
T=-78°C; 0.333333 h;
参考文献
Nieschalk, Jens; Batsanov, Andrei S.; O'Hagan, David; Howard, Judith A. K.
Tetrahedron, 1996 , vol. 52, # 1 p. 165 - 176
反应条件
1: (difluoromethyl)-phosphonic acid,diethyl ester With lithium diisopropyl amide in tetrahydrofuran; Petroleum ether
T=-78°C; Inert atmosphere;
2: chloro-trimethyl-silane in tetrahydrofuran; Petroleum ether
T=-78°C; 0.666667 h; Inert atmosphere;
参考文献
Alexandrova, Anastasia V.; Beier, Petr
Journal of Fluorine Chemistry, 2009 , vol. 130, # 5 p. 493 - 500
反应条件
in 1,4-dioxane
Ambient temperature;
参考文献
Burton, Donald J.; Takei, Ryutaro; Shin-Ya, Seiji
Journal of Fluorine Chemistry, 1981 , vol. 18, p. 197 - 202
反应条件
in 1,4-dioxane
Ambient temperature;
参考文献
Burton, Donald J.; Takei, Ryutaro; Shin-Ya, Seiji
Journal of Fluorine Chemistry, 1981 , vol. 18, p. 197 - 202
反应条件
in tetrahydrofuran
var. electrophiles; Product distribution;
参考文献
Obayashi, Michio; Ito, Eiji; Matsui, Kiyohide; Kondo, Kiyosi
Tetrahedron Letters, 1982 , vol. 23, # 22 p. 2323 - 2326
