三异丙基甲硅烷基三氟甲烷磺酸盐合成路线 （共 52 条）
反应条件
1: 1-(2-propyl-but-3-ynyl)-cyclohexene With lithium hexamethyldisilazane in tetrahydrofuran
T=-78°C;
2: With tBuOOLi in tetrahydrofuran; toluene
T=-78 - 0°C; 2.5 h;
3: tri-isopropylsylil trifluoromethane sulfonate in tetrahydrofuran; toluene
T=0°C; 0.5 h;
参考文献
Zhang, Liming; Sun, Jianwei; Kozmin, Sergey A.
Tetrahedron, 2006 , vol. 62, # 49 p. 11371 - 11380
反应条件
1: hex-1-en-5-yne With lithium hexamethyldisilazane in tetrahydrofuran
T=-78°C;
2: With tBuOOLi in tetrahydrofuran; toluene
T=-78 - 0°C; 2.5 h;
3: tri-isopropylsylil trifluoromethane sulfonate in tetrahydrofuran; toluene
T=0°C; 0.5 h;
参考文献
Zhang, Liming; Kozmin, Sergey A.
Journal of the American Chemical Society, 2004 , vol. 126, # 33 p. 10204 - 10205
反应条件
2,6-dimethylpyridine in dichloromethane
T=-78°C; 5 h;
参考文献
Corey, E. J.; Cho, Hidetsura; Ruecker, Christoph; Hua, Duy H.
Tetrahedron Letters, 1981 , vol. 22, # 36 p. 3455 - 3458
反应条件
triethylamine in dichloromethane
0.166667 h;
参考文献
Yu, Jin-Quan; Wu, Hai-Chen; Corey
Organic Letters, 2005 , vol. 7, # 7 p. 1415 - 1417
反应条件
triethylamine in dichloromethane
0.166667 h;
参考文献
Yu, Jin-Quan; Wu, Hai-Chen; Corey
Organic Letters, 2005 , vol. 7, # 7 p. 1415 - 1417
反应条件
1: 2-phenyl-1,3-dithiane With n-butyllithium in tetrahydrofuran; hexane
T=0°C; 0.166667 h;
2: tri-isopropylsylil trifluoromethane sulfonate in tetrahydrofuran; hexane
T=0 - 20°C;
参考文献
Svarovsky, Serge A.; Taraban, Marc B.; Barchi Jr., Joseph J.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 21 p. 3155 - 3161
反应条件
1: 87 percent / diethyl ether / -40 - 0 °C
2: n-butyllithium-tetramethylene diamine / diethyl ether / 2 h / -15 °C
View Scheme
参考文献
Corey, E. J.; Ruecker, Cristoph
Tetrahedron Letters, 1982 , vol. 23, # 7 p. 719 - 722
参考文献
Corey, E. J.; Ruecker, Cristoph
Tetrahedron Letters, 1982 , vol. 23, # 7 p. 719 - 722
反应条件
1: 87 percent / diethyl ether / -40 - 0 °C
2: n-butyllithium-tetramethylene diamine / diethyl ether / 2 h / -15 °C
3: 100 percent / 1 h / -78 - -40 °C
View Scheme
参考文献
Corey, E. J.; Ruecker, Cristoph
Tetrahedron Letters, 1982 , vol. 23, # 7 p. 719 - 722
反应条件
1.1: Cu(OAc)2*H2O; 2,2-bis[(3aS,8aR)-3a,8,8a-3H-indeno[3,2-d]oxazol-2yl]propane / ethanol / 120 h / 20 °C
1.2: 2,6-lutidine / CH2Cl2 / 16.5 h / 0 - 20 °C
1.3: HCO2NH4 / Pd/C / methanol / 24 h / 20 °C
2.1: 2.252 g / Et3N / CH2Cl2 / 70 h / 20 °C
3.1: 64 percent / (+/-)-camphorsulfonic acid; ethylene glycol / tetrahydrofuran / 48 h / 50 °C
4.1: 83 percent / TEMPO; sodium phosphate buffer; aq. NaClO2 / aq. NaOCl / acetonitrile / 4.5 h / 35 °C / pH 6.7
View Scheme
参考文献
Paintner, Franz F.; Allmendinger, Lars; Bauschke, Gerd; Klemann, Patricia
Organic Letters, 2005 , vol. 7, # 7 p. 1423 - 1426
