3-(三甲硅乙炔基)吡啶合成路线 （共 11 条）
反应条件
copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride; diisopropylamine T=30°C; 3 h;
参考文献
Holmes, Brian T.; Pennington, William T.; Hanks, Timothy W.
Synthetic Communications, 2003 , vol. 33, # 14 p. 2447 - 2461
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine T=20°C; 3 h;
参考文献
Feng, Yi-Si; Xie, Chuan-Qi; Qiao, Wen-Long; Xu, Hua-Jian
Organic Letters, 2013 , vol. 15, # 4 p. 936 - 939
反应条件
1: trimethylsilylacetylene With n-butyllithium in tetrahydrofuran; hexane T=0°C; 2: With zinc dibromide in tetrahydrofuran; hexane T=0°C; 3: pyridine-3-carbonitrile With n-tridecane; [NiCl2(PMe3)2] in tetrahydrofuran T=65°C; 20 h; Further stages.;
参考文献
Penney, Jonathan M.; Miller, Joseph A.
Tetrahedron Letters, 2004 , vol. 45, # 25 p. 4989 - 4992
反应条件
bis-triphenylphosphine-palladium(II) chloride 12 h; Heating;
参考文献
Gelman, Dmitri; Tsvelikhovsky, Dmitry; Molander, Gary A.; Blum, Jochanan
Journal of Organic Chemistry, 2002 , vol. 67, # 18 p. 6287 - 6290
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine in acetonitrile T=120°C; Sonogashira Cross-Coupling; 0.75 h; Microwave irradiation;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 7 p. 3033 - 3047
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine
参考文献
Phosphorus, Sulfur and Silicon and Related Elements, , vol. 168-169, p. 219 - 222
反应条件
1: potassium hydroxide / methanol; 4-(dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran / 20 °C / |Inert atmosphere 2: N-bromosuccinmide; silver nitrate / acetone / 20 °C / |Inert atmosphere View Scheme
参考文献
Ohmura, Toshimichi; Kijima, Akihito; Komori, Yusuke; Suginome, Michinori
Organic Letters, 2013 , vol. 15, # 14 p. 3510 - 3513
反应条件
potassium hydroxide in methanol; dichloromethane 2 h;
参考文献
Holmes, Brian T.; Pennington, William T.; Hanks, Timothy W.
Synthetic Communications, 2003 , vol. 33, # 14 p. 2447 - 2461
反应条件
potassium carbonate T=120 - 130°C; 0.25 h; microwave irradiation;
参考文献
Wettergren, Jenny; Minidis, Alexander B. E.
Tetrahedron Letters, 2003 , vol. 44, # 41 p. 7611 - 7612
反应条件
1: carbon dioxide; 3-((trimethylsilyl)ethynyl)pyridine With cesium fluoride in dimethyl sulfoxide
T=20°C; 3 h; Schlenk technique;
2: methyl iodide in dimethyl sulfoxide
T=20°C; 1 h;
参考文献
Yonemoto-Kobayashi, Misato; Inamoto, Kiyofumi; Tanaka, Yoshiyuki; Kondo, Yoshinori
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 23 p. 3773 - 3775
