(R)-(-)-2-氨基-1-己醇合成路线 (共 6 条)
反应条件
1: With hydrogenchloride in 1,4-dioxane; methanol T=20°C; 0.5 h; 2: With hydrogenchloride; hydrogen; 10percent Pd/C in 1,4-dioxane; methanol; ethyl acetate Further stages.;
参考文献
Journal of Organic Chemistry, , vol. 66, # 26 p. 8772 - 8778
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Heating;
参考文献
Peng, Jie; Barr, Mary E.; Ashburn, David A.; Odom, Jerome D.; Dunlap, R. Bruce; Silks, Louis A.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 4977 - 4987
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 59 ;
反应条件
1: ethanolic solution 2: sodium; ethanol View Scheme
参考文献
Journal of Biological Chemistry, , vol. 117, p. 709
反应条件
hydrogen iodide; acetic acid T=125°C; weitgehend racemisiertes (+)-2-Amino-hexan entsteht; folgende Hydrierung an Raney-Nickel in Methanol;
参考文献
Levene; Mardashew
Journal of Biological Chemistry, 1936 , vol. 117, p. 710
反应条件
T=125°C; Hydrieren des Reaktionsprodukts an Raney-Nickel in Methanol;
参考文献
Levene; Mardashew
Journal of Biological Chemistry, 1937 , vol. 117, p. 709