反应条件
1: 84 percent / H2 / 5percent Pd on charcoal / dimethylformamide / 20 h / 70 °C
2: 82 percent / Na2CO3 / 1,2-dichloro-benzene / 12 h / Heating
3: 1.) lithium di-isopropylamide, triethanolamine borate / 1.) THF, hexane, DMSO, -78 deg C, 2.) -20 deg C -> room temperature, 2 h
4: 1.) BF3-Et2O, 2.) bromine
5: 70 percent / selenium dioxide / dioxane / 96 h / Heating
View Scheme
参考文献
Preston, Peter N.; Will, Stephen G.; Winwick Thomas; Morley, John O.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 5 p. 1001 - 1007
