6,13-二溴-9,10-二甲氧基-1a,2,3,4,4a,5-六氢-1H-茚并[2,1-d]芴合成路线 （共 6 条）
反应条件
1: NaOH / aq. ethanol / 4.5 h / 20 °C
2: 78 percent / H2 / Raney nickel / acetone / 12 h / 20 °C
3: pyridine; Br2 / CH2Cl2 / -10 - 20 °C
4: 2.83 g / polyphosphoric acid / 6 h / 105 °C
View Scheme
参考文献
Venugopal, Murugapillai; Elango, Shanmugam; Parthiban, Anbanandam; Eni
Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3427 - 3431
反应条件
1: NaOH / aq. ethanol / 4.5 h / 20 °C
2: 78 percent / H2 / Raney nickel / acetone / 12 h / 20 °C
3: pyridine; Br2 / CH2Cl2 / -10 - 20 °C
4: 2.83 g / polyphosphoric acid / 6 h / 105 °C
View Scheme
参考文献
Venugopal, Murugapillai; Elango, Shanmugam; Parthiban, Anbanandam; Eni
Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3427 - 3431
反应条件
1: 78 percent / H2 / Raney nickel / acetone / 12 h / 20 °C
2: pyridine; Br2 / CH2Cl2 / -10 - 20 °C
3: 2.83 g / polyphosphoric acid / 6 h / 105 °C
View Scheme
参考文献
Venugopal, Murugapillai; Elango, Shanmugam; Parthiban, Anbanandam; Eni
Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3427 - 3431
参考文献
Venugopal, Murugapillai; Elango, Shanmugam; Parthiban, Anbanandam; Eni
Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3427 - 3431
反应条件
1: pyridine; Br2 / CH2Cl2 / -10 - 20 °C
2: 2.83 g / polyphosphoric acid / 6 h / 105 °C
View Scheme
参考文献
Venugopal, Murugapillai; Elango, Shanmugam; Parthiban, Anbanandam; Eni
Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3427 - 3431
反应条件
boron tribromide in dichloromethane
T=-78 - 20°C;
参考文献
Venugopal, Murugapillai; Elango, Shanmugam; Parthiban, Anbanandam; Eni
Tetrahedron Asymmetry, 2004 , vol. 15, # 21 p. 3427 - 3431
