1: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.5 h 2: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 3: 1.) 95 percent TFA / 1.) 2 h, 2.) water, G-15 Sephadex View Scheme

1: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 2: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.17 h 3: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 4: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.17 h 5: 4-(aminomethyl)piperidine / CHCl3 6: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.5 h 7: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 8: 1.) 95 percent TFA / 1.) 2 h, 2.) water, G-15 Sephadex View Scheme

1: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 2: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.17 h 3: 4-(aminomethyl)piperidine / CHCl3 4: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.5 h 5: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 6: 1.) 95 percent TFA / 1.) 2 h, 2.) water, G-15 Sephadex View Scheme

1: 4-(aminomethyl)piperidine / CHCl3 2: benzotriazolyloxy-tris(pyrrolidino)-phosphonium hexafluorophosphate, diisopropylethylamine / CHCl3 / 0.5 h 3: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 4: 1.) 95 percent TFA / 1.) 2 h, 2.) water, G-15 Sephadex View Scheme

1: 4-(aminomethyl)piperidine / CHCl3 / 0.5 h 2: 1.) 95 percent TFA / 1.) 2 h, 2.) water, G-15 Sephadex View Scheme

trifluoroacetic acid 1.) 2 h, 2.) water, G-15 Sephadex; Yield given. Multistep reaction;

in water T=37°C; 6 h; enzymes: leucine aminopeptidase , carboxypeptidase B; degradation in extracts of various mucosae (nasal, rectal, vaginal); female White Albino rabbits; different inhibitors (amastatin, thimerosal, thiorphan); pH=5-8; Product distributionRate constant;

in water T=37°C; 6 h; enzymes: leucine aminopeptidase , carboxypeptidase B; degradation in extracts of various mucosae (nasal, rectal, vaginal); female White Albino rabbits; different inhibitors (amastatin, thimerosal, thiorphan); pH=5-8; Product distributionRate constant;

in water T=37°C; 6 h; enzymes: leucine aminopeptidase , carboxypeptidase B; degradation in extracts of various mucosae (nasal, rectal, vaginal); female White Albino rabbits; different inhibitors (amastatin, thimerosal, thiorphan); pH=5-8; Product distributionRate constant;