2-(4-碘苯氧基)乙酸甲酯合成路线 （共 5 条）
反应条件
sodium hydroxide in ethanol T=25°C; 72 h;
参考文献
Mirk, Daniela; Waldvogel, Siegfried R.
Tetrahedron Letters, 2004 , vol. 45, # 42 p. 7911 - 7914
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
He, Yantao; Liu, Sijiu; Menon, Ambili; Stanford, Stephanie; Oppong, Emmanuel; Gunawan, Andrea M.; Wu, Li; Wu, Dennis J.; Barrios, Amy M.; Bottini, Nunzio; Cato, Andrew C. B.; Zhang, Zhong-Yin
Journal of Medicinal Chemistry, 2013 , vol. 56, # 12 p. 4990 - 5008
反应条件
sodium hydrogencarbonate in N,N-dimethyl-formamide
48 h;
参考文献
Malolanarasimhan, Krishnan; Kedei, Noemi; Sigano, Dina M.; Kelley, James A.; Lai, Christopher C.; Lewin, Nancy E.; Surawski, Robert J.; Pavlyukovets, Vladimir A.; Garfield, Susan H.; Wincovitch, Stephen; Blumberg, Peter M.; Marquez, Victor E.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 5 p. 962 - 978
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
LEO PHARMA A/S
Patent: US2012/101039 A1, 2012 ;
反应条件
hydrogen cation
T=30°C; Rate constant;
参考文献
Baliah, V.; Gurumurthy, R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 7 p. 629 - 631
