3-氨基-N-苯乙基苯甲酰胺合成路线 （共 3 条）
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 2 h;
参考文献
Mu; Coffing; Riese II; Geahlen; Verdier-Pinard; Hamel; Johnson; Cushman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 3 p. 441 - 452
反应条件
1.1: 100 percent / Et3N / dioxane; H2O / 24 h / 20 °C
2.1: EDCI; HOBt; Et3N / dimethylformamide / 24 h / 20 °C
2.2: 51 percent / dimethylformamide / 48 h / 20 °C
3.1: 100 percent / trifluoroacetic acid / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Mu; Coffing; Riese II; Geahlen; Verdier-Pinard; Hamel; Johnson; Cushman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 3 p. 441 - 452
反应条件
1.1: EDCI; HOBt; Et3N / dimethylformamide / 24 h / 20 °C
1.2: 51 percent / dimethylformamide / 48 h / 20 °C
2.1: 100 percent / trifluoroacetic acid / CH2Cl2 / 2 h / 20 °C
View Scheme
参考文献
Mu; Coffing; Riese II; Geahlen; Verdier-Pinard; Hamel; Johnson; Cushman
Journal of Medicinal Chemistry, 2001 , vol. 44, # 3 p. 441 - 452
