2-甲基-2-丙烯基乙酸酯合成路线 （共 57 条）
反应条件
isopropylmagnesium chloride; sodium hydride; Cl2Ni(1,2-bis(diphenylphosphino)ethane) in tetrahydrofuran
T=55°C; 18 h; Product distribution;
参考文献
Cuvigny, Therese; Julia, Marc
Journal of Organometallic Chemistry, 1986 , vol. 317, p. 383 - 408
反应条件
isopropylmagnesium chloride; sodium hydride; Cl2Ni(1,2-bis(diphenylphosphino)ethane) in tetrahydrofuran
T=160°C; 72 h; other temp./react. time; Product distribution;
参考文献
Cuvigny, Therese; Julia, Marc
Journal of Organometallic Chemistry, 1986 , vol. 317, p. 383 - 408
反应条件
1,1'-bis(diphenylphosphino)ferrocene-Pd in tetrahydrofuran
T=25°C; 5 h;
参考文献
Carfagna, C.; Mariani, L.; Musco, A.; Sallese, G.; Santi, R.
Journal of Organic Chemistry, 1991 , vol. 56, # 12 p. 3924 - 3927
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; triethylamine; lithium diisopropyl amide
Yield given. Multistep reaction;
参考文献
Funk, Raymond L.; Stallman, John B.; Wos, John A.
Journal of the American Chemical Society, 1993 , vol. 115, # 19 p. 8847 - 8848
反应条件
pyridine; NiI2; 4-chloro-2-(4,5-dihydro-1H-imidazol-2-yl)pyridine; tetrabutylammomium bromide; magnesium chloride; zinc in N,N-dimethyl acetamide
T=60°C; 12 h; Schlenk techniqueInert atmosphere; regioselective reaction;
参考文献
Cui, Xiaozhan; Wang, Shulin; Zhang, Yuwei; Deng, Wei; Qian, Qun; Gong, Hegui
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 19 p. 3094 - 3097
反应条件
dibenzoyl peroxide
T=100°C;
参考文献
Julia,M. et al.
Bulletin de la Societe Chimique de France, 1960 , p. 1735 - 1739
反应条件
1: Methallyl acetate With indium(III) chloride; dimethyl(n-butyl)amine; lithium chloride; indium; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=35°C;
2: 3-methoxy-iodobenzene in N,N-dimethyl-formamide
T=100°C;
参考文献
Seomoon, Dong; Lee, Kooyeon; Kim, Hyunseok; Lee, Phil Ho
Chemistry - A European Journal, 2007 , vol. 13, # 18 p. 5197 - 5206
反应条件
pyridine; NiI2; 4-chloro-2-(4,5-dihydro-1H-imidazol-2-yl)pyridine; tetrabutylammomium bromide; magnesium chloride; zinc in N,N-dimethyl acetamide
T=60°C; 12 h; Schlenk techniqueInert atmosphere; regioselective reaction;
参考文献
Cui, Xiaozhan; Wang, Shulin; Zhang, Yuwei; Deng, Wei; Qian, Qun; Gong, Hegui
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 19 p. 3094 - 3097
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
0.5 h; Ambient temperature;
参考文献
Tsuda, Tetsuo; Okada, Masahiro; Nishi, Sei-ichi; Saegusa, Takeo
Journal of Organic Chemistry, 1986 , vol. 51, # 4 p. 421 - 426
反应条件
indium(III) chloride; indium; lithium chloride; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in N,N-dimethyl-formamide
T=100°C; 2 h;
参考文献
Seomoon, Dong; Phil, Ho Lee
Journal of Organic Chemistry, 2008 , vol. 73, # 3 p. 1165 - 1168
