反式-1,4-二溴-2-丁烯合成路线 (共 96 条)
参考文献
Prevost; Valette
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1946 , vol. 222, p. 327
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Valette
Annales de Chimie (Cachan, France), 1948 , vol. <12>3, p. 674
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1946 , vol. 223, p. 908
参考文献
Lewina et al.
Zhurnal Obshchei Khimii, 1949 , vol. 19, p. 63,64
Chem.Abstr., 1949 , p. 6152
反应条件
in diethyl ether
24 h; Ambient temperature;
参考文献
Mesnard,D.; Miginiac,L.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1973 , vol. 277, p. 567 - 570
反应条件
T=24 - 27°C; Destillieren des Reaktionsprodukts;
参考文献
Sisido; Nozaki
Journal of the American Chemical Society, 1948 , vol. 70, p. 1609,1610, 1611
反应条件
1: (Z)-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester; 1,4-trans-dibromo-2-butene
2: hydrolysis;
3: decarboxylation;
参考文献
Holland, Joanne M.; Lewis, Mark; Nelson, Adam
Angewandte Chemie - International Edition, 2001 , vol. 40, # 21 p. 4082 - 4084
反应条件
(i), (ii) (hydrolysis), (iii) (decarboxylation); Multistep reaction;
参考文献
Corey,E.J.; Hamanaka,E.
Journal of the American Chemical Society, 1964 , vol. 86, p. 1641 - 1642
反应条件
1: diethyl malonate With sodium hydride in tetrahydrofuran
T=0°C; 2 h; Inert atmosphere;
2: 1,4-trans-dibromo-2-butene in tetrahydrofuran
T=0 - 20°C; Inert atmosphere;
参考文献
Sherry, Benjamin D.; Fuerstner, Alois
Chemical Communications, 2009 , # 46 p. 7116 - 7118
参考文献
Birch et al.
Journal of Organic Chemistry, 1958 , vol. 23, p. 1390
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Skinner et al.
Journal of the American Chemical Society, 1950 , vol. 72, p. 1648
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Kierstead et al.
Journal of the Chemical Society, 1952 , p. 3616,3619
反应条件
Reaktion der Natrium-Verbindung;
参考文献
Kierstead et al.
Journal of the Chemical Society, 1952 , p. 3616,3619
参考文献
Kierstead et al.
Journal of the Chemical Society, 1952 , p. 3616,3619