1,4-二氯-2-丁炔合成路线 （共 101 条）
反应条件
sodium amide 1.) liq. NH3, from -45 deg C to -35 deg C, 10 min, 2.) liq. NH3, from -44 deg C to -40 deg C; Yield given. Multistep reaction;
参考文献
Verkruijsse; Brandsma
Synthetic Communications, 1991 , vol. 21, # 1 p. 141 - 144
反应条件
anschliessendes Behandeln mit Jodmethan;
参考文献
Armitage et al.
Journal of the Chemical Society, 1951 , p. 44,47
Journal of the Chemical Society, 1952 , p. 1993,1996
反应条件
dihydrogen hexachloroplatinate in tetrahydrofuran react. of 1,4-dichlorobutyne, Et3GeH and H2PtCl6*6H2O in THF in an autoclave at 50°C for 4 h; distn. in vacuo, elem. anal.;
参考文献
Boukherroub, Rabah; Manuel, Georges
Journal of Organometallic Chemistry, 1993 , vol. 460, # 2 p. 155 - 162
反应条件
1: With 1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane in chloroform 18 h; Heating / reflux; 2: With hydrogenchloride in ethanol 18 h; Heating / reflux;
参考文献
G. D. Searle and Co.
Patent: US6344483 B1, 2002 ;
Location in patent: Page column 19 ;
反应条件
hydrogenchloride in ethanol; chloroform
参考文献
Akzo Nobel N.V.
Patent: US6410684 B1, 2002 ;
反应条件
diethyl ether T=-30°C;
参考文献
Lewina; Schabarow
Doklady Akademii Nauk SSSR, 1952 , vol. 84, p. 509
Chem.Abstr., 1953 , p. 3219
反应条件
sodium iodide in acetone T=20°C; 7.5 h;
参考文献
Cristau, H. J.; Plenat, F.; Duc, G.; Bennamara, A.
Tetrahedron, 1985 , vol. 41, # 13 p. 2717 - 2726
反应条件
(i) NaNH2, liq. NH3, Fe(NO3)2, (ii) /BRN= 505934/, Et2O, (iii) /BRN= 102378/; Multistep reaction;
参考文献
Riemschneider,R. et al.
Monatshefte fuer Chemie, 1965 , vol. 96, p. 1766 - 1780
反应条件
copper; copper(l) chloride; sodium chloride Reagens 4: wss. Salzsaeure;
参考文献
Kurtz et al.
Justus Liebigs Annalen der Chemie, 1959 , vol. 624, p. 1,19
反应条件
trichlorosilane; dihydrogen hexachloroplatinate in isopropyl alcohol
参考文献
Mamedov,M.A. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1965 , vol. 35, p. 461 - 466,458 - 461
