1: oxyde de diphenylphosphinomethylephenylcetone With sodium hydride in N,N-dimethyl-formamide T=20°C; 0.25 h; 2: n-dodecyl iodide in N,N-dimethyl-formamide T=80°C; 48 h; Further stages.;

1.1: n-BuLi / tetrahydrofuran / 0.25 h / 0 °C 1.2: 62 percent / tetrahydrofuran / 3 h / -78 °C 2.1: NaH / dimethylformamide; various solvent(s) / 0.25 h / 20 °C 2.2: 71 percent / dimethylformamide; various solvent(s) / 48 h / 80 °C View Scheme

1.1: n-BuLi / tetrahydrofuran / 0.25 h / 0 °C 1.2: 62 percent / tetrahydrofuran / 3 h / -78 °C 2.1: NaH / dimethylformamide; various solvent(s) / 0.25 h / 20 °C 2.2: 71 percent / dimethylformamide; various solvent(s) / 48 h / 80 °C View Scheme

sodium hydroxide in ethanol 3.5 h; Heating;