2-丙酮氧基-3,4-二氟硝基苯合成路线 （共 11 条）
反应条件
potassium carbonate; potassium iodide in acetone 4 h; Heating;
参考文献
Hayakawa; Hiramitsu; Tanaka
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 12 p. 4907 - 4913
反应条件
1: 29 percent / 10percent KOH / H2O; dimethylsulfoxide / 2 h / 18 - 20 °C 2: 65 percent / K2CO3, KI / acetone / 4 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 12 p. 4907 - 4913
反应条件
1: 90 percent / H2, Raney Ni / ethanol 2: 1 h / 140 - 145 °C 3: PPE / 1 h / 140 - 145 °C 4: 94 percent / conc. HCl / acetic acid / 3 h / Heating View Scheme
参考文献
Hayakawa; Hiramitsu; Tanaka
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 12 p. 4907 - 4913
反应条件
1: 90 percent / H2, Raney Ni / ethanol 2: 1 h / 140 - 145 °C 3: PPE / 1 h / 140 - 145 °C 4: 94 percent / conc. HCl / acetic acid / 3 h / Heating 5: 62 percent / dimethylsulfoxide / 12 h / 100 - 140 °C View Scheme
参考文献
Hayakawa; Hiramitsu; Tanaka
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 12 p. 4907 - 4913
反应条件
hydrogen; nickel in ethanol
参考文献
Hayakawa; Hiramitsu; Tanaka
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 12 p. 4907 - 4913
反应条件
hydrogen; triethylamine; palladium on activated charcoal in tetrahydrofuran T=20°C; P=760 Torr; 0.5 h; Product distribution; Further Variations:Reagents;
参考文献
Journal of Heterocyclic Chemistry, , vol. 39, # 5 p. 1065 - 1069
反应条件
1: 90 percent / H2, Raney Ni / ethanol 2: 1 h / 140 - 145 °C 3: PPE / 1 h / 140 - 145 °C 4: 94 percent / conc. HCl / acetic acid / 3 h / Heating 5: 53 percent / dimethylsulfoxide / 3 h / 100 - 140 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 32, # 12 p. 4907 - 4913
反应条件
1: 91 percent / p-TsOH / benzene / 18 h / Heating 2: 92 percent / H2 / 5percent Pd-C / ethanol / 4 h / Ambient temperature 3: 97 percent / 35percent HCl / 0.02 h / 80 °C View Scheme
参考文献
Atarashi; Tsurumi; Fujiwara; Hayakawa
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 2 p. 329 - 331
反应条件
hydrogen; triethylamine; palladium on activated charcoal in tetrahydrofuran T=20°C; P=760 Torr; 0.5 h; Product distribution; Further Variations:Reagents;
参考文献
Joung, Meyoung Ju; Ahn, Jin Hee; Kim, Hoe Moon; Kim, Kee Won; Kang, Jae Hoon; Lee, Seok Joon; Yoon, Nung Min
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 5 p. 1065 - 1069
反应条件
1: 90 percent / H2, Raney Ni / ethanol 2: 1 h / 140 - 145 °C 3: PPE / 1 h / 140 - 145 °C 4: 94 percent / conc. HCl / acetic acid / 3 h / Heating 5: 68 percent / dimethylsulfoxide / 5 h / 100 - 140 °C View Scheme
参考文献
Hayakawa; Hiramitsu; Tanaka
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 12 p. 4907 - 4913
