2-(1-甲基环己基)乙醇合成路线 （共 8 条）
反应条件
water; magnesium oxide
T=225°C;
参考文献
Schmerling
Journal of the American Chemical Society, 1949 , vol. 71, p. 698,700
反应条件
trimethylaluminum in hexane; dichloromethane
0.25 h;
参考文献
Snider, Barry B.; Cordova, Robert; Price, Robert T.
Journal of Organic Chemistry, 1982 , vol. 47, # 19 p. 3643 - 3646
反应条件
1.1: tetrahydrofuran / -5 - 0 °C
2.1: potassium hydroxide / ethanol / 13 h / Reflux
2.2: Acidic conditions
3.1: ethanol / 6 h / 160 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / -5 - 25 °C
View Scheme
参考文献
Kerns, Jeffrey K.; Nie, Hong; Bondinell, William; Widdowson, Katherine L.; Yamashita, Dennis S.; Rahman, Attiq; Podolin, Patricia L.; Carpenter, Donald C.; Jin, Qi; Riflade, Benoit; Dong, Xiaoyang; Nevins, Neysa; Keller, Paul M.; Mitchell, Laura; Tomaszek, Thaddeus
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4409 - 4415
反应条件
1: ethanol / 6 h / 160 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / -5 - 25 °C
View Scheme
参考文献
Kerns, Jeffrey K.; Nie, Hong; Bondinell, William; Widdowson, Katherine L.; Yamashita, Dennis S.; Rahman, Attiq; Podolin, Patricia L.; Carpenter, Donald C.; Jin, Qi; Riflade, Benoit; Dong, Xiaoyang; Nevins, Neysa; Keller, Paul M.; Mitchell, Laura; Tomaszek, Thaddeus
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4409 - 4415
反应条件
1.1: pyridine; titanium tetrachloride / tetrahydrofuran; tetrachloromethane / 72 h / 0 - 25 °C
2.1: tetrahydrofuran / -5 - 0 °C
3.1: potassium hydroxide / ethanol / 13 h / Reflux
3.2: Acidic conditions
4.1: ethanol / 6 h / 160 °C
5.1: lithium aluminium tetrahydride / tetrahydrofuran / -5 - 25 °C
View Scheme
参考文献
Kerns, Jeffrey K.; Nie, Hong; Bondinell, William; Widdowson, Katherine L.; Yamashita, Dennis S.; Rahman, Attiq; Podolin, Patricia L.; Carpenter, Donald C.; Jin, Qi; Riflade, Benoit; Dong, Xiaoyang; Nevins, Neysa; Keller, Paul M.; Mitchell, Laura; Tomaszek, Thaddeus
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4409 - 4415
反应条件
1.1: potassium hydroxide / ethanol / 13 h / Reflux
1.2: Acidic conditions
2.1: ethanol / 6 h / 160 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / -5 - 25 °C
View Scheme
参考文献
Kerns, Jeffrey K.; Nie, Hong; Bondinell, William; Widdowson, Katherine L.; Yamashita, Dennis S.; Rahman, Attiq; Podolin, Patricia L.; Carpenter, Donald C.; Jin, Qi; Riflade, Benoit; Dong, Xiaoyang; Nevins, Neysa; Keller, Paul M.; Mitchell, Laura; Tomaszek, Thaddeus
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4409 - 4415
反应条件
in hexane; dichloromethane
0.25 h;
参考文献
Snider, Barry B.; Cordova, Robert; Price, Robert T.
Journal of Organic Chemistry, 1982 , vol. 47, # 19 p. 3643 - 3646
参考文献
Schmerling
Journal of the American Chemical Society, 1949 , vol. 71, p. 698,700
