2-溴-4-甲基-6-硝基苯胺合成路线 （共 12 条）
反应条件
bromine; acetic acid 0.5 h;
参考文献
Yasui, Yoshizumi; Frantz, Derik K.; Siegel, Jay S.
Organic Letters, 2006 , vol. 8, # 22 p. 4989 - 4992
反应条件
nitric acid Destillieren des entstandenen Acetylderivates mit Natronlauge;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 192, p. 203
参考文献
Journal of the Chemical Society, , vol. 105, p. 514
参考文献
Journal of the Chemical Society, , p. 918
参考文献
Journal of the Chemical Society, , p. 918
参考文献
Chemische Berichte, , vol. 13, p. 963
Chemische Berichte, , vol. 14, p. 417
反应条件
sulfuric acid; sodium nitrite in ethanol T=73 - 78°C;
参考文献
Procopiou, Panayiotis A.; Barrett, Victoria J.; Ford, Alison J.; Looker, Brian E.; Lunniss, Gillian E.; Needham, Deborah; Smith, Claire E.; Somers, Graham
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 20 p. 6026 - 6032
反应条件
1: 1.) conc. H2SO4, NaNO2, 2.) 50percent H3PO2, Cu2O / 1.) H2O, -2 deg C - -3 deg C, 2 h, 2.) H2O, -5 deg C, 90 min; 0 deg C, 10 min 2: 59 percent / dimethylformamide / 6 h / Heating View Scheme
参考文献
Fisher; Dershem; Prewitt
Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 1040 - 1043
反应条件
1: 1.) conc. H2SO4, NaNO2, 2.) 50percent H3PO2, Cu2O / 1.) H2O, -2 deg C - -3 deg C, 2 h, 2.) H2O, -5 deg C, 90 min; 0 deg C, 10 min 2: 59 percent / dimethylformamide / 6 h / Heating 3: 75 percent / 75percent H2SO4 / H2O / 1 h / 150 °C View Scheme
参考文献
Adams; Rinehart
Journal of Antibiotics, 1994 , vol. 47, # 12 p. 1456 - 1465
反应条件
Diazotization.Reaktion ueber mehrere Stufen;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 192, p. 210
