9-芴甲基-N-琥珀酰亚胺基碳酸酯合成路线 （共 303 条）
反应条件
1: L-Glu-γ--tert-butyl ester With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
sodium carbonate in water; acetone Acylation; 1 h;
参考文献
Wiejak, Stanislaw; Masiukiewicz, Elzbieta; Rzeszotarska, Barbara
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 10 p. 1489 - 1490
反应条件
sodium carbonate in N,N-dimethyl-formamide 0.166667 h; Ambient temperature;
参考文献
Lapatsanis, Lucas; Milias, George; Froussios, Kleanthis; Kolovos, Miltiadis
Synthesis, 1983 , # 8 p. 671 - 673
反应条件
1: [35S]-L-(-)-Methionine With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
1: L-aspartic acid β-t-butyl ester With N,N-dicyclohexylamine in acetone T=20°C; 2: 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]-2,5-pyrrolidinedione With sodium carbonate in water; acetonitrile T=0 - 20°C; pH=8; 3: With potassium hydrogensulfate in water; acetonitrile pH=2 - 3;
参考文献
Nowshuddin, Shaik; Rao; Reddy, A. Ram
Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
反应条件
1: With sodium carbonate in tetrahydrofuran; water 48 h; 2: With hydrogenchloride in tetrahydrofuran; water pH=2 - 3;
参考文献
Tetrahedron Asymmetry, , vol. 22, # 6 p. 613 - 618
反应条件
1: CH2Cl2 / 1.5 h / Ambient temperature 2: MeOH / CH2Cl2 / 0.5 h / Ambient temperature View Scheme
参考文献
Organic Preparations and Procedures International, , vol. 30, # 2 p. 183 - 186
反应条件
anhydrous calcium nitrate; triethylamine in N,N-dimethyl-formamide T=20°C; Substitution; 2 h;
参考文献
Raydnov, M. G.; Klimenko, L. V.; Mitin, Yu. V.
Russian Journal of Bioorganic Chemistry, 1999 , vol. 25, # 5 p. 283 - 287
Bioorganicheskaya Khimiya, 1999 , vol. 25, # 5 p. 323 - 328
反应条件
sodium hydrogencarbonate
参考文献
European Journal of Organic Chemistry, , # 20-21 p. 3685 - 3689
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water T=20°C; 22 h;
参考文献
Moussa, Amer; Meffre, Patrick; Martinez, Jean; Rolland, Valerie
Amino Acids, 2012 , vol. 42, # 4 p. 1339 - 1348
