反应条件
1: 51 percent / N-bromophthalimide / benzene 2: 98 percent / H2SO4 / dioxane 3: 1.) NaH / 1.) THF, 0 deg C, 10 min, 2.) THF, RT, 2 h 4: 98 percent / 1 N aq. NaOH / ethanol / 1 h / Ambient temperature 5: 73 percent / sodium bis(2-methoxyethoxy)aluminum hydride / toluene / 0.25 h / 85 °C View Scheme
参考文献
Atwal, Karnail S.; Ferrara, Francis N.; Ding, Charles Z.; Grover, Gary J.; Sleph, Paul G.; Dzwonczyk, Steven; Baird, Anne J.; Normandin, Diane E.
Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 304 - 313
