2-羟基-1,4-萘醌合成路线 （共 313 条）
反应条件
1-[hydroxy(tosyloxy)iodo]-1H,1H-perfluoroethane in dichloromethane 2 h; Ambient temperature;
参考文献
Papoutsis, Ioannis; Spyroudis, Spyros; Varvoglis, Anastasios; Callies, Jeffrey A.; Zhdankin, Viktor V.
Tetrahedron Letters, 1997 , vol. 38, # 48 p. 8401 - 8404
反应条件
1: in 1,4-dioxane Knoevenagel condensation; Reflux; 2: With sulfuric acid in 1,4-dioxane T=20°C; 0.5 h;
参考文献
Ferreira, Sabrina Baptista; Kaiser, Carlos Roland; Ferreira, Vitor Francisco
Organic Preparations and Procedures International, 2009 , vol. 41, # 3 p. 211 - 215
反应条件
1: 40 percent / lithium hydride / dimethylsulfoxide / 45 deg C, 5 h; 25 deg C, 10 h 2: H2SO4 / H2O / 25 °C View Scheme
参考文献
Schaffner-Sabba, Karl; Schmidt-Ruppin, Karl H.; Wehrli, Walter; Schuerch, ALfred R.; Wasley, Jan W. F.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 990 - 994
反应条件
in 1,4-dioxane Knoevenagel condensation; Reflux;
参考文献
Ferreira, Sabrina Baptista; Kaiser, Carlos Roland; Ferreira, Vitor Francisco
Organic Preparations and Procedures International, 2009 , vol. 41, # 3 p. 211 - 215
反应条件
diethyl ether; acetic acid T=90°C;
参考文献
Fieser et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3177
反应条件
(i) SOCl2, (ii) aq. H2O2, Py, (iii) /BRN= 1565260/; Multistep reaction;
参考文献
Bullock
Journal of medicinal chemistry, 1968 , vol. 11, # 3 p. 419 - 424
反应条件
triethylamine in diethyl ether 5 h; Ambient temperature;
参考文献
Brahmeshwari, G.; Rao, V. Rajeswar; Rao, T. V. Padmanabha
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995 , vol. 34, # 2 p. 139 - 140
反应条件
(i) SOCl2, (ii) aq. H2O2, Py, (iii) /BRN= 1565260/; Multistep reaction;
参考文献
Bullock
Journal of medicinal chemistry, 1968 , vol. 11, # 3 p. 419 - 424
参考文献
Neunhoeffer; Weise
Chemische Berichte, 1938 , vol. 71, p. 2703,2707
反应条件
sodium hydride in toluene 24 h; Heating;
参考文献
Yamaguchi; Katsuki; Yokoyama; Hirai
Journal of Heterocyclic Chemistry, 2001 , vol. 38, # 2 p. 511 - 514
