2-羟基-1,4-萘醌合成路线 （共 313 条）
反应条件
1: 85 percent / 1.) K2CO3 / 1.) acetone, 45 deg C, 1 h, 2.) acetone, 2 h
View Scheme
参考文献
Wurm, Gotthard; Geres, Uwe
Archiv der Pharmazie (Weinheim, Germany), 1984 , vol. 317, # 7 p. 606 - 609
参考文献
Fieser; Oxford
Journal of the American Chemical Society, 1942 , vol. 64, p. 2063
参考文献
Fieser et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3177
反应条件
silver(l) oxide in chloroform
参考文献
Laaatsch
1983 , vol. NO. 11, p. 1886 - 1900
反应条件
1: methyl vinyl sulphone With bromine in dichloromethane
6 h; Reflux;
2: 2-hydroxynaphthalene-1,4-dione With 1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran; dichloromethane
6.83333 h; Cooling with iceReflux;
参考文献
Zhoushan HaiZhongZhou Xinsheng Pharmaceuticals Co., Ltd.; Jiang, Zhiwei; Wang, Aijin; Li, Xian; Li, Qingrong; Hu, Hongwei; Xu, Jiali; Hu, Yuesong; Ye, Yan
Patent: US2013/150437 A1, 2013 ;
Location in patent: Paragraph 0153 ;
反应条件
potassium iodide; potassium hydroxide in water
4 h; Reflux;
参考文献
Tseng, Chih-Hua; Lin, Chang-Sheng; Shih, Pin-Keng; Tsao, Lo-Ti; Wang, Jih-Pyang; Cheng, Chih-Mei; Tzeng, Cherng-Chyi; Chen, Yeh-Long
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 18 p. 6773 - 6779
反应条件
1: 35.2 percent / ceric ammonium nitrate / acetonitrile / 1 h / 0 °C
2: 64.7 percent / lithium bis(trimethylsilyl)amide / tetrahydrofuran / 0.25 h / -78 °C
View Scheme
参考文献
Lee, Yong Rok; Kim, Byung So; Jung, Yong Ug; Koh, Wha Soo; Cha, Jin Soon; Kim, Nam Woo
Synthetic Communications, 2002 , vol. 32, # 20 p. 3099 - 3105
反应条件
in neat (no solvent)
T=100°C; P=750.075 Torr; 0.05 h; Microwave irradiation;
参考文献
Devi Bala, Balasubramanian; Muthusaravanan, Sivasubramanian; Perumal, Subbu
Tetrahedron Letters, 2013 , vol. 54, # 29 p. 3735 - 3739
反应条件
1: hydrochloric acid
2: glacial acetic acid
View Scheme
参考文献
Fieser
Journal of the American Chemical Society, 1926 , vol. 48, p. 2927,2929
Journal of the American Chemical Society, 1928 , vol. 50, p. 439,443
参考文献
Elsbach
Chemische Berichte, 1882 , vol. 15, p. 689
