1-(2,4-二硝基苯基)哌啶合成路线 （共 93 条）
反应条件
2-hydroxy-pyridine in benzene
T=25°C; other catalysts, other solvents, var. conc. of catalysts; Rate constant;
参考文献
Forlani, Luciano; Marianucci, Elisabetta; Todesco, Paolo E.
Gazzetta Chimica Italiana, 1992 , vol. 122, # 9 p. 349 - 353
反应条件
tetrabutyl ammonium fluoride in N,N-dimethyl-formamide
T=20°C; Substitution; 4 h; UV-irradiation;
参考文献
Huertas, Inma; Gallardo, Iluminada; Marquet, Jordi
Tetrahedron Letters, 2000 , vol. 41, # 2 p. 279 - 281
参考文献
Le Fevre; Saunders; Turner
Journal of the Chemical Society, 1927 , p. 1171
Full Text Show Details
Groves; Turner; Sharp
Journal of the Chemical Society, 1929 , p. 521
反应条件
sodium hydroxide in 1,4-dioxane; water
T=30°C; ionic strength O.1M (NaCl); reaction the absence of NaOH, NaOH concentration dependence; aminodephenoxylation with pyrrolidine and piperidine and hydroxydephenylation with NaOH of substituted diphenyl ethers; Rate constantMechanism;
参考文献
Bunnett, Joseph F.; Cartano, Artemio V.
Journal of the American Chemical Society, 1981 , vol. 103, # 16 p. 4861 - 4865
参考文献
Titskii, G. D.; Mitchenko, E. S.
Journal of Organic Chemistry USSR (English Translation), 1988 , vol. 24, # 10 p. 1949 - 1954
Zhurnal Organicheskoi Khimii, 1988 , vol. 24, # 10 p. 2161 - 2166
参考文献
Cahn
Journal of the Chemical Society, 1931 , p. 1121
反应条件
1: triethylamine / N,N-dimethyl-formamide / 80 °C / |Inert atmosphere
2: ethanol; water / 25 °C / pH 11.12
View Scheme
参考文献
Aguayo, Raul; Arias, Felipe; Canete, Alvaro; Zuniga, Carolina; Castro, Enrique A.; Pavez, Paulina; Santos, Jose G.
International Journal of Chemical Kinetics, 2013 , vol. 45, # 3 p. 202 - 211
反应条件
triethylamine in benzene
T=25°C; var. oxygen- and nitrogen-containing bases; Rate constantMechanism;
参考文献
Vizgert, R. V.; Sheiko, S. G.; Kulishova, T. P.; Sukharevskaya, L. E.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 6.1 p. 1048 - 1052
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 6 p. 1164 - 1169
反应条件
triethylamine in benzene
T=25°C; var. oxygen and nitrogen-containing bases; Rate constantMechanism;
参考文献
Vizgert, R. V.; Sheiko, S. G.; Kulishova, T. P.; Sukharevskaya, L. E.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 6.1 p. 1048 - 1052
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 6 p. 1164 - 1169
反应条件
1: 100 percent / diethyl ether / Ambient temperature
2: 35.1 percent / acetonitrile / 24 h / Ambient temperature
View Scheme
参考文献
Vizgert, R. V.; Sheiko, S. G.; Kulishova, T. P.; Pekhtereva, T. M.; Nardekova, V. V.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, p. 166 - 169
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 1 p. 185 - 189
