N-苄基-4-氰基-4-(1-哌啶)-哌啶合成路线 （共 6 条）
反应条件
N,N-dimethyl acetamide; magnesium sulfate T=55°C; 48 h;
参考文献
US2007/219214 A1, ;
Page/Page column 27 ;
US 20070219214 A1
反应条件
in methanol; water T=20°C; 48 h;
参考文献
US2004/180890 A1, ;
Page/Page column 4; 12 ;
US 20040180890 A1
参考文献
US5780466 A1, ;
US 5780466 A
反应条件
in methanol 2 h; Heating;
参考文献
Iorio; Molinari; Scotti de Carolis; Niglio
Farmaco, Edizione Scientifica, 1984 , vol. 39, # 7 p. 599 - 611
反应条件
1: 67 percent / methanol; H2O / Ambient temperature 2: 74 percent / methanol / 2 h / Heating View Scheme
参考文献
Farmaco, Edizione Scientifica, , vol. 39, # 7 p. 599 - 611
反应条件
1: With sulfuric acid in water T=100°C; 0.166667 h; Heating / reflux; 2: With sodium hydroxide in water T=0°C; pH=9;
参考文献
Solvay pharmaceuticals GmbH
Patent: US2007/219214 A1, 2007 ;
Location in patent: Page/Page column 27 ;
US 20070219214 A1
