2-苯甲酰基-1-氰基-1,2-二氢异喹啉合成路线 （共 61 条）
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hung; Mooney; Prager; Ward
Australian Journal of Chemistry, 1981 , vol. 34, # 1 p. 151 - 162
反应条件
1: 49 percent / sodium hydride / dimethylformamide / 6 h / -20 °C
2: 1.) KOH; 2.) hydrochloric acid / 1.) ethanol, water, reflux, 5 h; 2.) reflux, 1 h
View Scheme
参考文献
Kerekes, P.; Gaal, Gy.; Bognar, R.; Toeroe, T.; Costisella, B.
Acta Chimica Academiae Scientiarum Hungaricae, 1980 , vol. 105, # 4 p. 283 - 292
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hung; Mooney; Prager; Ward
Australian Journal of Chemistry, 1981 , vol. 34, # 1 p. 151 - 162
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Hung; Mooney; Prager; Ward
Australian Journal of Chemistry, 1981 , vol. 34, # 1 p. 151 - 162
反应条件
1: dioxane; phenyl lithium; diethyl ether / Reagens 4: Acrylonitril, Reagens 5: festes CO2, Reagens 6: H2O
2: phosphorus oic acid
View Scheme
参考文献
Boekelheide; Godfrey
Journal of the American Chemical Society, 1953 , vol. 75, p. 3679,3682
反应条件
1: With sodium hydride in N,N-dimethyl-formamide
T=-10°C; 4 h;
2: With sodium hydroxide; ethanol; water
Heating / reflux;
参考文献
UNIVERSITE DE LIEGE
Patent: US2009/93517 A1, 2009 ;
Location in patent: Page/Page column 8 ;
US 20090093517 A1
反应条件
1,4-dioxane; diethyl ether; phenyllithium
Behandeln der Reaktionsloesung mit Aethylacrylat;
参考文献
Boekelheide; Godfrey
Journal of the American Chemical Society, 1953 , vol. 75, p. 3679,3682
参考文献
Boekelheide; Godfrey
Journal of the American Chemical Society, 1953 , vol. 75, p. 3679,3682
反应条件
diethyl ether; phenyllithium
Behandeln des Reaktionsgemisches mit Benzylbromid und Erwaermen des Reaktionsprodukts mit wss.-aethanol. Kalilauge;
参考文献
Boekelheide; Weinstock
Journal of the American Chemical Society, 1952 , vol. 74, p. 660,663
反应条件
1: 98 percent / dimethylformamide / 1 h / 20 °C
2: 92 percent / KOH
View Scheme
参考文献
Reimann; Hoglmuller
Archiv der Pharmazie, 1985 , vol. 318, # 6 p. 487 - 495
