1-甲基-1H-吡唑-5-羰酰氯合成路线 （共 4 条）
反应条件
thionyl chloride in ethyl acetate T=80°C; 5 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2530078 A1, 2012 ;
Location in patent: Page/Page column 72 ;
反应条件
N,N-dimethyl-formamide in tetrahydrofuran T=20°C; 2 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 15 p. 4714 - 4729
反应条件
lithium aluminium tetrahydride in methanol 0.666667 h; Heating;
参考文献
Perevalov, V. P.; Karim, A. K. Kh.; Andreeva, M. A.; Rumyantsev, E. G.; Stepanov, B. I.
J. Gen. Chem. USSR (Engl. Transl.), 1982 , vol. 52, # 11 p. 2598 - 2605,2297 - 2303
反应条件
1: diethyl ether; ethanol / 20 °C 2: hydrogenchloride / water / |Reflux View Scheme
参考文献
Taydakov, Ilya; Krasnoselskiy, Sergey
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 6 p. 1422 - 1424
